Parkinsonism in Ontario: Comorbidity associated with hospitalization in a large cohort

被引:69
作者
Guttman, M
Slaughter, PM
Theriault, ME
DeBoer, DP
Naylor, CD
机构
[1] Univ Toronto, Dept Med, Div Neurol, Toronto, ON, Canada
[2] ICES, Toronto, ON, Canada
[3] Univ Toronto, Fac Med, Deans Off, Toronto, ON, Canada
关键词
parkinsonism; comorbidity; hospitalization;
D O I
10.1002/mds.10648
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
To study comorbidity in patients with Parkinsonism (PKM), relative hospitalization rates from 1994 to 1999 for 15,304 cases were compared with 30,608 controls. After correction for differential survival, the rates were higher for cases compared to controls for aspiration pneumonia (6.34; 95% confidence interval [CI], 5.23, 7.93), affective psychosis (2.71; 95% CI, 2.13, 3.32), hip fractures (2.56; 95% CI, 2.35, 2.76), other urinary tract disorders including infections (2.5; 95% CI, 2.17, 2.86), septicemia (2.39; 95% CI, 2.02, 2.85) and fluid and electrolyte disorders (2.27; 95% CI, 1.93,2.66). The rates for cardiac, cerebrovascular, and peripheral vascular disease were similar. Preventive measures and aggressive management of these conditions as outpatients may reduce the rates of hospitalization and improve the morbidity and mortality of PKM. (C) 2003 Movement Disorder Society.
引用
收藏
页码:49 / 53
页数:5
相关论文
共 12 条
[1]   SURVIVAL AND CAUSE OF DEATH IN A COHORT OF PATIENTS WITH PARKINSONISM - POSSIBLE CLUES TO ETIOLOGY [J].
BENSHLOMO, Y ;
MARMOT, MG .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1995, 58 (03) :293-299
[2]   AN ESTIMATE OF THE INCIDENCE OF DEPRESSION IN IDIOPATHIC PARKINSONS-DISEASE [J].
DOONEIEF, G ;
MIRABELLO, E ;
BELL, K ;
MARDER, K ;
STERN, Y ;
MAYEUX, R .
ARCHIVES OF NEUROLOGY, 1992, 49 (03) :305-307
[3]   PARKINSONS-DISEASE AND ITS COMORBID DISORDERS - AN ANALYSIS OF MICHIGAN MORTALITY DATA, 1970 TO 1990 [J].
GORELL, JM ;
JOHNSON, CC ;
RYBICKI, BA .
NEUROLOGY, 1994, 44 (10) :1865-1868
[4]   Burden of parkinsonism: A population-based study [J].
Guttman, M ;
Slaughter, PM ;
Theriault, ME ;
DeDoer, DP ;
Naylor, CD .
MOVEMENT DISORDERS, 2003, 18 (03) :313-319
[5]   Parkinsonism in Ontario: Physician utilization [J].
Guttman, M ;
Slaughter, PM ;
Theriault, ME ;
DeBoer, DP ;
Naylor, CD .
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2002, 29 (03) :221-226
[6]   Parkinsonism in Ontario - Increased mortality compared with controls in a large cohort study [J].
Guttman, M ;
Slaughter, PM ;
Theriault, ME ;
DeBoer, DP ;
Naylor, CD .
NEUROLOGY, 2001, 57 (12) :2278-2282
[7]   A 10-year study of the incidence of and factors predicting dementia in Parkinson's disease [J].
Hughes, TA ;
Ross, HF ;
Musa, S ;
Bhattacherjee, S ;
Nathan, RN ;
Mindham, RHS ;
Spokes, EGS .
NEUROLOGY, 2000, 54 (08) :1596-1602
[8]   Combined effect of age and severity on the risk of dementia in Parkinson's disease [J].
Levy, G ;
Schupf, N ;
Tang, MX ;
Cote, LJ ;
Louis, ED ;
Mejia, H ;
Stern, Y ;
Marder, K .
ANNALS OF NEUROLOGY, 2002, 51 (06) :722-729
[9]   The impact of comorbid disease and injuries on resource use and expenditures in parkinsonism [J].
Pressley, JC ;
Louis, ED ;
Tang, MX ;
Cote, L ;
Cohen, PD ;
Glied, S ;
Mayeux, R .
NEUROLOGY, 2003, 60 (01) :87-93
[10]   Comorbidity of the nonmotor symptoms of Parkinson's disease [J].
Shulman, LM ;
Taback, RL ;
Bean, J ;
Weiner, WJ .
MOVEMENT DISORDERS, 2001, 16 (03) :507-510