Activation-induced cytidine deaminase structure and functions: A species comparative view

被引：31

作者：

Barreto, Vasco M. ^{[1
]}

Magor, Brad G. ^{[2
]}

机构：

[1] Inst Gulbenkian Ciencias, P-2780156 Oeiras, Portugal

[2] Univ Alberta, Dept Biol Sci, Edmonton, AB T6G 2E5, Canada

来源：

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY | 2011年 / 35卷 / 09期

基金：

加拿大自然科学与工程研究理事会;

关键词：

Activation-induced cytidine deaminase; AID; Immunoglobulin; Somatic hypermutation; Class switch recombination; Evolution; Review; CLASS-SWITCH RECOMBINATION; IMMUNOGLOBULIN HEAVY-CHAIN; DNA-POLYMERASE-ETA; SINGLE-STRANDED-DNA; PROTEIN-KINASE-A; VARIABLE LYMPHOCYTE RECEPTORS; SOMATIC HYPERMUTATION; B-CELL; ANTIBODY DIVERSIFICATION; GENE CONVERSION;

D O I：

10.1016/j.dci.2011.02.005

中图分类号：

S9 [水产、渔业];

学科分类号：

0908 ;

摘要：

In the ten years since the discovery of activation-induced cytidine deaminase (AID) there has been considerable effort to understand the mechanisms behind this enzyme's ability to target and modify immunoglobulin genes leading to somatic hypermutation and class switch recombination. While the majority of research has focused on mouse and human models of AID function, work on other species, from lamprey to rabbit and sheep, has taught us much about the scope of functions of the AID mutator. This review takes a species-comparative approach to what has been learned about the AID mutator enzyme and its role in humoral immunity. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：991 / 1007

页数：17

共 50 条

[41] The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies
Luo, ZH
Ronai, D
Scharff, MD
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 114 (04) : 726 - 735
[42] Targeting Activation-Induced Cytidine Deaminase Overcome Tumor Evasion of Immunotherapy by CTLs
Liu, Jin-Qing
Joshi, Pramod S.
Wang, Chuansong
El-Omrani, Hani Y.
Xiao, Yi
Liu, Xiuping
Hagan, John P.
Liu, Chang-Gong
Wu, Lai-Chu
Bai, Xue-Feng
JOURNAL OF IMMUNOLOGY, 2010, 184 (10) : 5435 - 5443
[43] Expression of activation-induced cytidine deaminase splicing variants in patients with ankylosing spondylitis
Kim, Ji-Young
Yoon, Hee-Kyung
Song, Seung Taek
Park, Seok-Rae
Shim, Seung-Cheol
AUTOIMMUNITY, 2017, 50 (08) : 435 - 440
[44] Cloning and expression of activation induced cytidine deaminase from Bos taurus
Verma, Subhash
Goldammer, Tom
Aitken, Robert
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2010, 134 (3-4) : 151 - 159
[45] Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination
Han, Li
Masani, Shahnaz
Yu, Kefei
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (28) : 11584 - 11589
[46] Activation-induced cytidine deaminase expression in colorectal cancer
Li, Lanlan
Su, Nana
Cui, Min
Li, Hong
Zhang, Qian
Yu, Ning
Wu, Shuhua
Cao, Zhang
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2019, 12 (11): : 4119 - 4124
[47] Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5
Pavri, Rushad
Gazumyan, Anna
Jankovic, Mila
Di Virgilio, Michela
Klein, Isaac
Ansarah-Sobrinho, Camilo
Resch, Wolfgang
Yamane, Arito
San-Martin, Bernardo Reina
Barreto, Vasco
Nieland, Thomas J.
Root, David E.
Casellas, Rafael
Nussenzweig, Michel C.
CELL, 2010, 143 (01) : 122 - 133
[48] Activation-induced cytidine deamlinase: Structure-function relationship as based on the study of mutants
Durandy, Anne
Peron, Sophie
Taubenheim, Nadine
Fischer, Alain
HUMAN MUTATION, 2006, 27 (12) : 1185 - 1191
[49] Activation-induced cytidine deaminase: in sickness and in health
Leonardo Alves de Souza Rios
Benjamin Cloete
Shaheen Mowla
Journal of Cancer Research and Clinical Oncology, 2020, 146 : 2721 - 2730
[50] Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID
Wakae, K
Magor, BG
Saunders, H
Nagaoka, H
Kawamura, A
Kinoshita, K
Honjo, T
Muramatsu, M
INTERNATIONAL IMMUNOLOGY, 2006, 18 (01) : 41 - 47

← 1 2 3 4 5 →