The morphometric analysis of serotonin granules of platelets in migraine

被引：0

作者：

Issati-Zade, K. F. ^{[1
]}

Chetvertnykh, V. A. ^{[1
]}

Shutov, A. A. ^{[1
]}

机构：

[1] Perm State Med Acad, Fac Med, Chair Hist, VP Chair Neurol, Perm, Russia

来源：

ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA | 2011年 / 111卷 / 10期

关键词：

migraine; serotonin; platelets;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The serotonin hypothesis of migraine attack is based on a phenomenon of fast and significant decreasing of serotonin granules in blood platelets. The morphometric analysis was used to study area, diameter, length and wideness of platelet serotonin granules in 20 migraine patients during a headache attack and in an interparoxysmal period. We found that the area of serotonin granule surface in platelets was 0.231 +/- 0.595 mcm during the migraine attack that was significantly higher than that during the interparoxysmal period (0.205 +/- 0.037 mcm) and in the platelets of healthy controls (0.190 +/- 0.028 mcm) (n=10). The study has shown that during migraine attack serotonin granules are undergone also structural changes.

引用

页码：58 / 61

页数：4

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