Practical synthesis of amides from alkynyl bromides, amines, and water

被引：69

作者：

Chen, Zheng-Wang ^{[1
,2
]}

Jiang, Huan-Feng ^{[1
]}

Pan, Xiao-Yan ^{[1
]}

He, Zai-Jun ^{[1
]}

机构：

[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

[2] Gannan Teachers Coll, Dept Biol & Chem, Ganzhou 341000, Peoples R China

来源：

TETRAHEDRON | 2011年 / 67卷 / 33期

基金：

中国国家自然科学基金;

关键词：

ONE-POT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; OXIDATIVE AMIDATION; CATALYZED AMIDATION; N-ALKYNYLATION; BOND FORMATION; THIO ACIDS; ALDEHYDES; AZIDES; LIGATION;

D O I：

10.1016/j.tet.2011.06.045

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general and efficient method for the synthesis of a wide range of amides is described here. The reactions were conducted under convenient conditions and provided secondary and tertiary amides in moderate to excellent yields. A variety of amines and substituted alkynyl bromides were used to investigate the scope of the reactions. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：5920 / 5927

页数：8

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