Diagnosis of Castleman Disease

被引：41

作者：

Szalat, Raphael ^{[1
]}

Munshi, Nikhil C. ^{[1
,2
]}

机构：

[1] Dana Farber Canc Inst, Med Oncol, 450 Brookline Ave,M230, Boston, MA 02215 USA

[2] VA Boston Healthcare Syst, 1400 VFW Pkwy, West Roxbury, MA USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2018年 / 32卷 / 01期

关键词：

Castleman disease a Diagnosis; HHV8; POEMS; TAFRO; Paraneoplastic pemphigus; LYMPH-NODE HYPERPLASIA; PARANEOPLASTIC PEMPHIGUS; POEMS-SYNDROME; LYMPHOPROLIFERATIVE SYNDROME; RENAL INVOLVEMENT; HIV-INFECTION; FEATURES; HHV-8; RISK;

D O I：

10.1016/j.hoc.2017.09.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Castleman disease (CD) is a rare and heterogenous group of disorders sharing in common an abnormal lymph node pathology. CD comprises distinct subtypes with different prognoses. Unicentric CD and multicentric CD are featured by specific systemic manifestations and may be associated with Kaposi sarcoma, non-Hodgkin and Hodgkin lymphoma, and POEMS syndrome. Multicentric CD is classically associated with systemic symptoms and poorer prognosis. In this article, the authors review how to diagnose the disease, keeping in context the clinical findings, biochemical changes, and complications associated with CD.

引用

页码：53 / +

页数：13

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