Attention deficit hyperactivity disorder (ADHD) is one of the most common behavioral disorders in children. Symptoms of ADHD include hyperactivity, low frustration tolerance, impulsivity, and inattention. While the biological pathways leading to ADHD are not clearly delineated, a number of genetic and environmental risk factors for the disorder are recognized. In the early 1970s, research conducted by Dr. Benjamin Feingold found that when hyperactive children were given a diet free of artificial food additives and dyes, symptoms of hyperactivity were reduced. While some clinical studies supported these findings, more rigorous empirical studies conducted over the next 20 years were less positive. As a result, research on the role of food additives in contributing to ADHD waned. In recent years, however, interest in this area has revived. In response to more recent research and public petitions, in December 2009 the British government requested that food manufacturers remove most artificial food dyes from their products. While these strictures could have positive effects on behavior, the removal of food dyes is not a panacea for ADHD, which is a multifaceted disorder with both biological and environmental underpinnings. (C) 2011 International Life Sciences Institute
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Univ Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, ItalyUniv Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, Italy
Curatolo, Paolo
Paloscia, Claudio
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Univ Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, ItalyUniv Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, Italy
Paloscia, Claudio
D'Agati, Elisa
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Univ Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, ItalyUniv Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, Italy
D'Agati, Elisa
Moavero, Romina
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Univ Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, ItalyUniv Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, Italy
Moavero, Romina
Pasini, Augusto
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Univ Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, ItalyUniv Roma Tor Vergata, Pediat Neurol Unit, Dept Neurosci, I-00133 Rome, Italy
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Royal Childrens Hosp, Parkville, Vic 3052, Australia
Univ Melbourne, Murdoch Childrens Res Inst, Melbourne, Vic 3010, Australia
Univ Melbourne, Dept Pediat, Melbourne, Vic 3010, AustraliaRoyal Childrens Hosp, Parkville, Vic 3052, Australia
Efron, Daryl
Hazell, Philip
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Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia
Univ Sydney, Infant Child & Adolescent Mental Hlth Serv, Sydney South West Area Hlth Serv, Sydney, NSW 2006, Australia
Thomas Walker Hosp Rivendell Child, Adolescent & Family Mental Hlth Serv, Sydney, NSW, AustraliaRoyal Childrens Hosp, Parkville, Vic 3052, Australia
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Northwell, 2000 Marcus Ave,Suite 300, New Hyde Pk, NY 11042 USA
Cohen Childrens Med Ctr, Queens, NY USANorthwell, 2000 Marcus Ave,Suite 300, New Hyde Pk, NY 11042 USA
Caterfino, Andrew
Krishna, Shruthi
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Northwell, 2000 Marcus Ave,Suite 300, New Hyde Pk, NY 11042 USA
Cohen Childrens Med Ctr, Queens, NY USANorthwell, 2000 Marcus Ave,Suite 300, New Hyde Pk, NY 11042 USA
Krishna, Shruthi
Chen, Victoria
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Northwell, 2000 Marcus Ave,Suite 300, New Hyde Pk, NY 11042 USA
Cohen Childrens Med Ctr, Queens, NY USANorthwell, 2000 Marcus Ave,Suite 300, New Hyde Pk, NY 11042 USA
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Antalya Training & Res Hosp, Dept Child & Adolescent Psychiat, Antalya, TurkeyAntalya Training & Res Hosp, Dept Child & Adolescent Psychiat, Antalya, Turkey
Gunay Ay, Merve
Kilic, Birim Gunay
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Ankara Univ, Sch Med, Dept Child & Adolescent Psychiat, Ankara, TurkeyAntalya Training & Res Hosp, Dept Child & Adolescent Psychiat, Antalya, Turkey