Moxifloxacin penetration in bronchial secretions of mechanically ventilated patients with pneumonia

被引：16
|
作者：
Leone, M
Albanèse, J
Sampol-Manos, E
Simon, N
Lacarelle, B
Bruguerolle, B
Martin, C
机构：
[1] Nord Hosp, Dept Anesthesiol, Marseille, France
[2] Nord Hosp, Intens Care Unit, Marseille, France
[3] Nord Hosp, Ctr Trauma, Marseille, France
[4] Timone Hosp, Marseiles Sch Med, Dept Pharmacokinet, Marseille, France
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 02期
关键词：
D O I：
10.1128/AAC.48.2.638-640.2004
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The pharmacokinetics of moxifloxacin was studied in 17 mechanically ventilated patients with pneumonia. Patients were given 400 mg of moxifloxacin intravenously. Blood samples and bronchial secretions were taken on days 1 and 4. A dose of 400 mg of moxifloxacin allows one to achieve efficient concentrations in bronchial secretions and plasma.
引用
收藏
页码：638 / 640
页数：3
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