NKT cell frequency in Japanese type 1 diabetes

被引：9
|
作者：
Oikawa, Y [1 ]
Shimada, A [1 ]
Yamada, S [1 ]
Motohashi, Y [1 ]
Nakagawa, Y [1 ]
Irie, J [1 ]
Maruyama, T [1 ]
Saruta, T [1 ]
机构：
[1] Keio Univ, Sch Med, Div Endocrinol & Metab, Dept Internal Med,Shinjuku Ku, Tokyo 1608582, Japan
来源：
IMMUNOLOGY OF DIABETES II: PATHOGENESIS FROM MOUSE TO MAN | 2003年 / 1005卷
关键词：
type; 1; diabetes; NKT cell;
D O I：
10.1196/annals.1288.033
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A numerical and functional deficit of natural killer T (NKT) cells has been reported to be associated with the pathogenesis of Caucasian patients with type 1 diabetes. However, a conflicting finding of a higher frequency of NKT cells (Valpha24+ Vbeta11+ T cells) was observed in islet-associated Ab+ and Ab- Japanese "classic" type I diabetes. Here, we combined the data of NKT cell frequency in Ab+ and Ab- "classic" type 1 diabetic patients and then analyzed the relationship between NKT cell frequency and disease activity.
引用
收藏
页码：230 / 232
页数：3
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