Cancer- and Chemotherapy-Induced Anemia

被引：150

作者：

Rodgers, George M., III ^{[1
]}

Becker, Pamela Sue ^{[2
]}

Blinder, Morey ^{[3
,4
]}

Cella, David ^{[5
]}

Chanan-Khan, Asher ^{[6
]}

Cleeland, Charles ^{[7
]}

Coccia, Peter F. ^{[8
]}

Djulbegovic, Benjamin ^{[9
]}

Gilreath, Jeffrey A. ^{[1
]}

Kraut, Eric H. ^{[10
,11
]}

Matulonis, Ursula A. ^{[12
]}

Millenson, Michael M. ^{[13
]}

Reinke, Denise ^{[14
]}

Rosenthal, Joseph ^{[15
]}

Schwartz, Rowena N. ^{[16
]}

Soff, Gerald ^{[17
]}

Stein, Richard S. ^{[18
]}

Vlahovic, Gordana

Weir, Alva B., III ^{[19
]}

机构：

[1] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[2] Univ Washington, Seattle Canc Care Alliance, Seattle, WA 98195 USA

[3] Washington Univ, Sch Med, St Louis, MO 63130 USA

[4] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA

[5] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[6] Roswell Pk Canc Inst, Buffalo, NY USA

[7] Univ Texas MD Anderson Canc Ctr, Houston, TX USA

[8] Nebraska Med Ctr, UNMC Eppley Canc Ctr, Omaha, NE USA

[9] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[10] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Columbus, OH 43210 USA

[11] Solove Res Inst, Columbus, OH USA

[12] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[13] Fox Chase Canc Ctr, Philadelphia, PA USA

[14] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[15] City Hope Comprehens Canc Ctr, Duarte, CA USA

[16] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

[17] Mem Sloan Kettering Canc Ctr, New York, NY USA

[18] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[19] Univ Tennessee, Inst Canc, St Jude Childrens Res Hosp, Knoxville, TN 37996 USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2012年 / 10卷 / 05期

关键词：

ERYTHROPOIESIS-STIMULATING AGENTS; RED-CELL APLASIA; PHASE-III TRIAL; NONHEMOLYTIC TRANSFUSION REACTIONS; PLACEBO-CONTROLLED TRIALS; ADVERSE DRUG EVENTS; PATIENT-LEVEL DATA; QUALITY-OF-LIFE; EVERY; WEEKS; DARBEPOETIN-ALPHA;

D O I：

10.6004/jnccn.2012.0064

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Anemia is prevalent in 30% to 90% of patients with cancer. Anemia can be corrected through either treating the underlying cause or providing supportive care through transfusion with packed red blood cells or administration of erythropoiesis-stimulating agents (ESAs), with or without iron supplementation. Recent studies showing detrimental health effects of ESAs sparked a series of FDA label revisions and a sea change in the perception of these once commonly used agents. In light of this, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Cancer- and Chemotherapy-Induced Anemia underwent substantial revisions this year. The purpose of these NCCN Guidelines is twofold: 1) to operationalize the evaluation and treatment of anemia in adult cancer patients, with an emphasis on those who are receiving concomitant chemotherapy, and 2) to enable patients and clinicians to individualize anemia treatment options based on patient condition. (JNCCN 2012;10:628-653)

引用

页码：628 / +

页数：13

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