SOLVENT-FREE C-BENZOYLATION AND N-BENZOYLATION REACTIONS USING MICROWAVE HEATING

被引：8

作者：

Al-Masum, Mohammad ^{[1
]}

Wai, Maya Chen ^{[1
]}

Dunnenberger, Henry ^{[1
]}

机构：

[1] Tennessee State Univ, Dept Chem, Nashville, TN 37209 USA

来源：

SYNTHETIC COMMUNICATIONS | 2011年 / 41卷 / 19期

关键词：

Catalyst-free and solvent-free N-benzoylation; microwave heating; solvent-free AlCl3-catalyzed C-benzoylation; SUPPORTED REAGENTS; ORGANIC-SYNTHESIS; ACYLATION; IRRADIATION; CATALYSIS; EFFICIENT; PEPTIDE; DESIGN; ESTERS; ACID;

D O I：

10.1080/00397911.2010.515363

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An ecofriendly and efficient microwave-irradiated solvent-free benzoylation method was developed. The procedure for C-benzoylation used 50 mol% AlCl3 as a Lewis acid catalyst at 130 degrees C and was completed in 10 min. The isolated yield was between 71% and 100%. N-benzoylation was conducted in a catalyst-free environment at 130 degrees C in 10 min. The isolated yield was between 80% and 100%.

引用

页码：2888 / 2898

页数：11

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