Near-infrared excitation/emission microscopy with lanthanide-based nanoparticles

被引:11
作者
Frances-Soriano, Laura [1 ,2 ]
Ferrera-Gonzalez, Juan [1 ]
Gonzalez-Bejar, Maria [1 ]
Perez-Prieto, Julia [1 ]
机构
[1] Univ Valencia, Inst Ciencia Mol ICMol, Dept Quim Organ, Catedrat Jose Beltran 2, Valencia 46980, Spain
[2] Univ Rouen Normandie, Lab COBRA Chim Organ Bioorgan Reactivite & Anal, CNRS, INSA, F-76821 Mont St Aignan, France
基金
欧盟地平线“2020”;
关键词
Lanthanide-doped nanoparticles; Optical microscopy; NIR-I/NIR-II light; Lifetime imaging microscopy; Super-resolution microscopy; UP-CONVERSION NANOPARTICLES; UPCONVERTING NANOPARTICLES; SUPERRESOLUTION MICROSCOPY; FLUORIDE NANOPARTICLES; PHOTODYNAMIC THERAPY; GOLD NANOPARTICLES; RECENT PROGRESS; LUMINESCENCE; SHELL; EMISSION;
D O I
10.1007/s00216-022-03999-4
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Near-infrared optical imaging offers some advantages over conventional imaging, such as deeper tissue penetration, low or no autofluorescence, and reduced tissue scattering. Lanthanide-doped nanoparticles (LnNPs) have become a trend in the field of photoactive nanomaterials for optical imaging due to their unique optical features and because they can use NIR light as excitation and/or emission light. This review is focused on NaREF4 NPs and offers an overview of the state-of-the-art investigation in their use as luminophores in optical microscopy, time-resolved imaging, and super-resolution nanoscopy based on, or applied to, LnNPs. Secondly, whenever LnNPs are combined with other nanomaterial or nanoparticle to afford nanohybrids, the characterization of their physical and chemical properties is of current interest. In this context, the latest trends in optical microscopy and their future perspectives are discussed.
引用
收藏
页码:4291 / 4310
页数:20
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