A functional genomics approach to identify pathways of drug resistance in medulloblastoma

被引：11
|
作者：
Bertrand, Kelsey C. [1 ,2 ,3 ]
Faria, Claudia C. [4 ]
Skowron, Patryk [5 ,6 ,7 ,8 ]
Luck, Amanda [5 ,6 ,7 ,8 ]
Garzia, Livia [5 ,6 ,7 ,8 ]
Wu, Xiaochong [5 ,6 ,7 ,8 ]
Agnihotri, Sameer [9 ]
Smith, Christian A. [5 ,6 ,7 ,8 ]
Taylor, Michael D. [5 ,6 ,7 ,8 ]
Mack, Stephen C. [1 ,2 ,3 ]
Rutka, James T. [5 ,6 ,7 ,8 ]
机构：
[1] Baylor Coll Med, Dept Pediat, Div Hematol & Oncol, Houston, TX 77030 USA
[2] Texas Childrens Hosp, Canc Ctr, Brain Tumor Program, Houston, TX 77030 USA
[3] Texas Childrens Hosp, Hematol Ctr, Brain Tumor Program, Houston, TX 77030 USA
[4] Ctr Hosp Lisboa Norte, Hosp Santa Maria, Dept Neurosurg, EPE, Lisbon, Portugal
[5] Hosp Sick Children, Dept Dev & Stem Cell Biol & Regenerat Med, Toronto, ON, Canada
[6] Hosp Sick Children, Arthur & Sonia Labatt Brain Tumor Res Ctr, Toronto, ON, Canada
[7] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada
[8] Hosp Sick Children, Dept Neurosurg, Toronto, ON, Canada
[9] Univ Pittsburgh, Childrens Hosp, Sch Med, Dept Neurol Surg, Pittsburgh, PA 15260 USA
来源：
ACTA NEUROPATHOLOGICA COMMUNICATIONS | 2018年 / 6卷
基金：
美国国家卫生研究院;
关键词：
Cancer; Brain tumor; Medulloblastoma; Drug resistance; Functional genomics; Transposon mutagenesis; Sleeping beauty; MOLECULAR SUBGROUPS; LANDSCAPE; MUTATIONS; ACVR1;
D O I：
10.1186/s40478-018-0652-8
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
引用
收藏
页数：6
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