Efficient microwave-assisted synthesis of aminoxy acid conjugates

被引：7
|
作者：
Draghici, Bogdan [1 ]
Hansen, Finn K. [1 ]
Buciumas, Ana-Maria [1 ]
El-Gendy, Bahaa El-Dien M. [1 ,2 ]
Todadze, Ekaterina [1 ]
Katritzky, Alan R. [1 ,3 ]
机构：
[1] Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA
[2] Benha Univ, Dept Chem, Fac Sci, Banha 13511, Egypt
[3] King Abdulaziz Univ, Dept Chem, Jeddah 21589, Saudi Arabia
来源：
RSC ADVANCES | 2011年 / 1卷 / 04期
关键词：
PHASE SYNTHESIS; PEPTIDES; ARCHITECTURE;
D O I：
10.1039/c1ra00413a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A representative set of Cbz-protected (alpha-aminoxyacyl) benzotriazoles was utilized as versatile building blocks for the efficient and convenient synthesis of novel alpha-aminoxy acid conjugates. Convenient protocols were developed for their regioselective preparation with sterically hindered nucleophiles such as sugars, terpenes, steroids and nucleosides.
引用
收藏
页码：602 / 606
页数：5
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