Primary intraventricular Glioblastoma GBM: Case report and review of literature

Introduction and importance: Glioblastoma multiforme (GBM) is the most common primary central nervous system tumor. The frontotemporal location is the most common location for the occurrence of GBM, however, the occurrence of this lesion in the intraventricular system is very rare and only a few cases have been reported about it in the literature.Case presentation: We present another case of primary intraventricular GBM of a 61-year-old patient with a detailed description of the clinical presentation, neuro-radiological and pathological findings, and the surgical approach to the tumor. Clinical discussion: We reviewed cases of primary intraventricular glioblastomas in the literature and concluded that it is very rare and has poor prognosis. Surgical gross debulking and the extent resection are very important factors that affect the prognosis of GBM patients.Conclusion: Intraventricular GBM is an aggressive tumor with a challenging location that is usually associated with a poor prognosis. However, our patient showed a long-term survival of 78 months. (c) 2022 The Author(s). Published by Elsevier Ltd on behalf of Surgical Associates Ltd.