Hydrolysis of esters and amides by the metallo nucleophile Tp(Cum,Me)Zn-OH

被引：28

作者：

Ruf, M ^{[1
]}

Vahrenkamp, H ^{[1
]}

机构：

[1] UNIV FREIBURG,INST ANORGAN & ANALYT CHEM,D-79104 FREIBURG,GERMANY

来源：

CHEMISCHE BERICHTE | 1996年 / 129卷 / 09期

关键词：

zinc hydroxide complexes; pyrazolylborate ligand; hydrolysis of esters and amides;

D O I：

10.1002/cber.19961290908

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The molecular zinc hydroxide complex Tp(Cum,Me)Zn-OH [1, Tp(Cum,Me) = tris(3-cumenyl-5-methylpyrazolyl)hydroborate] is a powerful nucleophile. It effects stoichiometric hydrolysis of activated esters RCO-OX and amides RCO-NHX in nonaqueous media. The cleavage products are Tp(Cum,Me)Zn-OCOR and HOX or H(2)NX, resp. Two of them (Tp(Cum,Me)Zn-OCO-CH2-CH2OH resulting from propiolactone and Tp(Cum,Me)Zn-OCO-CF3 resulting from trifluoroacetamide) were characterized by crystal structure determinations.

引用

页码：1025 / 1028

页数：4

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