Using Principles of Behavioral Epigenetics to Advance Research on Early-Life Stress

被引：16
作者：
Conradt, Elisabeth [1 ]
机构：
[1] Univ Utah, Salt Lake City, UT USA
来源：
CHILD DEVELOPMENT PERSPECTIVES | 2017年 / 11卷 / 02期
关键词：
behavioral epigenetics; early-life stress; DNA methylation; RECEPTOR GENE PROMOTER; DNA METHYLATION; DIFFERENTIAL SUSCEPTIBILITY; MATERNAL STRESS; CHILD-ABUSE; ENVIRONMENT; NR3C1; REPLICATION; ASSOCIATION; PERSPECTIVE;
D O I：
10.1111/cdep.12219
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
While the negative effects of early-life stress on children's developmental outcomes are well documented, we know little about how these processes unfold and which children are more susceptible to these exposures. In this article, I outline how studying the effects of early-life stress on children's development can be advanced by considering how epigenetic processes may contribute to the emergence of children's behavior. The study of epigenetics can help pinpoint the mechanisms by which early-life stress may affect developmental outcomes and identify which children may be most sensitive to the effects of these exposures. I conclude by highlighting the challenges inherent in studying epigenetics in children and offer possible solutions.
引用
收藏
页码：107 / 112
页数：6
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