Sarcoidosis Manifesting as Cardiac Sarcoidosis and Massive Splenomegaly

被引：5

作者：

Kawano, Sayaka ^{[1
]}

Kato, Johji ^{[2
]}

Kawano, Noriaki ^{[3
]}

Yoshimura, Yuki ^{[4
]}

Masuyama, Hiroyuki ^{[4
]}

Fukunaga, Takashi ^{[4
]}

Shimao, Yoshiya ^{[5
]}

Mihara, Kenroh ^{[6
]}

Ueda, Akira ^{[3
]}

Toyoda, Kiyokazu ^{[7
]}

Imamura, Takuroh ^{[1
]}

Kitamura, Kazuo ^{[1
]}

机构：

[1] Miyazaki Univ, Dept Internal Med Circulatory & Body Fluid Regula, Fac Med, Miyazaki, Japan

[2] Miyazaki Univ, Frontier Sci Res Ctr, Miyazaki, Japan

[3] Miyazaki Prefectural Hosp, Dept Internal Med, Miyazaki, Japan

[4] Miyazaki Prefectural Hosp, Dept Cardiol, Miyazaki, Japan

[5] Miyazaki Prefectural Hosp, Dept Pathol, Miyazaki, Japan

[6] Miyazaki Prefectural Hosp, Clin Lab, Miyazaki, Japan

[7] Miyazaki Prefectural Hosp, Dept Surg, Miyazaki, Japan

来源：

INTERNAL MEDICINE | 2012年 / 51卷 / 01期

关键词：

cardiac sarcoidosis; massive splenomegaly; pacemaker; splenectomy; prednisolone;

D O I：

10.2169/internalmedicine.51.5247

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sarcoidosis is a multisystemic granulomatous disease of unknown etiology. We report an unusual case of sarcoidosis in a woman presenting with cardiac sarcoidosis and massive splenomegaly with a familial history of cardiac sarcoidosis. Cardiac sarcoidosis was diagnosed based on electrocardiogram, echocardiogram, (18)F-fluoro-2-deoxyglucose positron emission tomography ((18)F-FDG-PET) and skin histological findings. We performed splenectomy to rule out malignant lymphoma, and histological findings confirmed sarcoidosis. After splenectomy, we initiated prednisolone therapy. After 20 months of diagnosis, she was symptom free. Echocardiography and (18)F-FDG-PET may be a key diagnostic tool and prednisolone therapy may be safe, effective, and feasible for cardiac sarcoidosis.

引用

页码：65 / 69

页数：5

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