A regiospecific three-component one-step cyclocondensation to 6-cyano-5,8-dihydropyrido[2,3-d]pyrimidin-4(3H)-ones using microwaves under solvent-free conditions

被引：73
作者：
Quiroga, J
Cisneros, C
Insuasty, B
Abonía, R
Nogueras, M
Sánchez, A
机构：
[1] Univ Valle, Dept Chem, Grp Invest Compuestos Heterociclicos, Cali, Colombia
[2] Univ Jaen, Dept Inorgan & Organ Chem, Jaen 23071, Spain
来源：
TETRAHEDRON LETTERS | 2001年 / 42卷 / 33期
关键词：
D O I：
10.1016/S0040-4039(01)01092-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In a solvent-free system, regiospecific three-component one-step cyclocondensation to dihydropyrido[2.3-d]pyrimidin-4(3H)-ones 4 starting front readily available aminopyrimidin-4-ones 1, benzoylacetonitrile 2 and benzaldehydes 3 by microwave radiation was carried out. This rapid method produces pure products in high yields (70-75%). (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：5625 / 5627
页数：3
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