What is new in tics, dystonia and chorea?

被引:6
作者
Macerollo, Antonella [1 ]
Martino, Davide [2 ,3 ]
机构
[1] UCL, Inst Neurol, London, England
[2] Kings Coll Hosp NHS Trust, Natl Parkinson Fdn Int Ctr Excellence, London, England
[3] Lewisham & Greenwich NHS Trust, Queen Elizabeth Hosp, London, England
关键词
Chorea; diagnosis; dystonia; hyperkinetic movement disorders; tics; treatments; DEEP-BRAIN-STIMULATION; TOURETTE-SYNDROME; BEHAVIOR-THERAPY; GLOBUS-PALLIDUS; DOUBLE-BLIND; DISORDERS; DIAGNOSIS; PHENOMENOLOGY; CLASSIFICATION; PREVALENCE;
D O I
10.7861/clinmedicine.16-4-383
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Movement disorders comprise hyperkinetic involuntary movements (eg tremor, myoclonus, tics, dystonia and chorea) and hypokinetic (parkinsonism) disorders. Tics are cardinal features of primary tic disorders encompassing Tourette syndrome (TS), but are also found in some neurodegenerative conditions and may be induced by psychoactive substances. The first line treatment for tics is pharmacological (mainly dopamine receptor blockers or alpha-2 adrenergic agonists) and behavioural. Dystonia and chorea syndromes are considerably heterogeneous in aetiology, and age at onset, body distribution of the movement disorder, accompanying neurological motor and non-motor features, and systemic manifestations are all important to reach a correct aetiological diagnosis. While symptomatic pharmacological treatment remains the mainstay of treatment for choreas, deep brain stimulation surgery has a well-defined place in the management of medically refractory dystonia.
引用
收藏
页码:383 / 389
页数:7
相关论文
共 45 条
[1]   The clinical approach to movement disorders [J].
Abdo, Wilson F. ;
van de Warrenburg, Bart P. C. ;
Burn, David J. ;
Quinn, Niall P. ;
Bloem, Bastiaan R. .
NATURE REVIEWS NEUROLOGY, 2010, 6 (01) :29-37
[2]   Double-blind clinical trial of thalamic stimulation in patients with Tourette syndrome [J].
Ackermans, Linda ;
Duits, Annelien ;
van der Linden, Chris ;
Tijssen, Marina ;
Schruers, Koen ;
Temel, Yasin ;
Kleijer, Mariska ;
Nederveen, Pieter ;
Bruggeman, Richard ;
Tromp, Selma ;
van Kranen-Mastenbroek, Vivianne ;
Kingma, Herman ;
Cath, Danielle ;
Visser-Vandewalle, Veerle .
BRAIN, 2011, 134 :832-844
[3]   A systematic review on the diagnosis and treatment of primary (idiopathic) dystonia and dystonia plus syndromes:: report of an EFNS/MDS-ES Task Force [J].
Albanese, A. ;
Barnes, M. P. ;
Bhatia, K. P. ;
Fernandez-Alvarez, E. ;
Filippini, G. ;
Gasser, T. ;
Krauss, J. K. ;
Newton, A. ;
Rektor, I. ;
Savoiardo, M. ;
Valls-Sole, J. .
EUROPEAN JOURNAL OF NEUROLOGY, 2006, 13 (05) :433-444
[4]   EFNS guidelines on diagnosis and treatment of primary dystonias [J].
Albanese, A. ;
Asmus, F. ;
Bhatia, K. P. ;
Elia, A. E. ;
Elibol, B. ;
Filippini, G. ;
Gasser, T. ;
Krauss, J. K. ;
Nardocci, N. ;
Newton, A. ;
Valls-Sole, J. .
EUROPEAN JOURNAL OF NEUROLOGY, 2011, 18 (01) :5-18
[5]   Phenomenology and classification of dystonia: A consensus update [J].
Albanese, Alberto ;
Bhatia, Kailash ;
Bressman, Susan B. ;
DeLong, Mahlon R. ;
Fahn, Stanley ;
Fung, Victor S. C. ;
Hallett, Mark ;
Jankovic, Joseph ;
Jinnah, Hyder A. ;
Klein, Christine ;
Lang, Anthony E. ;
Mink, Jonathan W. ;
Teller, Jan K. .
MOVEMENT DISORDERS, 2013, 28 (07) :863-873
[6]   Is this Dystonia? [J].
Albanese, Alberto ;
Lalli, Stefania .
MOVEMENT DISORDERS, 2009, 24 (12) :1725-1731
[7]  
[Anonymous], MOV DISORD
[8]   Dystonia: an update on phenomenology, classification, pathogenesis and treatment [J].
Balint, Bettina ;
Bhatia, Kailash P. .
CURRENT OPINION IN NEUROLOGY, 2014, 27 (04) :468-476
[9]   Paroxysmal Dyskinesias [J].
Bhatia, Kailash P. .
MOVEMENT DISORDERS, 2011, 26 (06) :1157-1165
[10]  
BURNETT L, 1992, CURR OPIN NEUROL NEU, V5, P308