IN VITRO STUDY OF COLLAGEN COATING BY ELECTRODEPOSITION ON ACRYLIC BONE CEMENT WITH ANTIMICROBIAL POTENTIAL

被引：0
作者：
Cavalu, S. [1 ]
Simon, V. [2 ,3 ]
Banica, F. [1 ]
机构：
[1] Univ Oradea, Fac Med & Pharm, Oradea 410068, Romania
[2] Univ Babes Bolyai, Fac Phys, Cluj Napoca 400084, Romania
[3] Univ Babes Bolyai, Inst Interdisciplinary Res Bionanosci, Cluj Napoca 400084, Romania
来源：
DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES | 2011年 / 6卷 / 01期
关键词：
Bone cement; Antimicrobial agent; Collagen coating; SILVER ION RELEASE; MICROSTRUCTURE;
D O I：
暂无
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
New acrylic bone cements were prepared by incorporating silver oxide as potential antimicrobial agent in a polymethyl metacrylate (PMMA) matrix. In order to improve the biomineralisation and biocompatibitity of these cements, electrolytic deposition of collagen was performed in a three-electrode electrochemistry system. ATR FTIR and FT Raman analyses demonstrated that collagen adsorption depends on the silver content in samples. In vitro tests, performed in simulated body fluid (SBF) during three weeks of SBF incubation, revealed the release of Ag+ by a mechanism involving Ca2+ and Na+ ions exchange. The mineralization process upon incubation was confirmed by the ATR FTIR spectra, which evidenced the phosphate characteristic bands of hydroxyapatite, depending on the silver oxide content in the samples.
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页码：89 / 97
页数：9
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