A complementary new drug for PNH

被引：7

作者：

Brodsky, Robert A. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Baltimore, MD 21218 USA

来源：

BLOOD | 2020年 / 135卷 / 12期

关键词：

D O I：

10.1182/blood.2020004959

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this issue of Blood, Roth et al show in a phase 1/2 trial that crovalimab, a subcutaneously administered monoclonal antibody that targets C5, is safe and effective in treating paroxysmal nocturnal hemoglobinuria (PNH).(1) Crovalimab targets a C5 epitope that is different from the IV C5 inhibitors, eculizumab and ravulizumab. Crovalimab is administered subcutaneously every 4 weeks.

引用

页码：884 / 885

页数：3

共 9 条

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