Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332

被引：163
|
作者：
Zhao, Yao [1 ,2 ]
Fang, Chao [3 ]
Zhang, Qi [1 ,2 ,4 ,5 ]
Zhang, Ruxue [6 ]
Zhao, Xiangbo [3 ]
Duan, Yinkai [1 ,2 ]
Wang, Haofeng [1 ,2 ]
Zhu, Yan [1 ,2 ]
Feng, Lu [1 ,2 ]
Zhao, Jinyi [1 ,2 ]
Shao, Maolin [1 ,2 ]
Yang, Xiuna [1 ,2 ]
Zhang, Leike [6 ]
Peng, Chao [7 ]
Yang, Kailin [8 ]
Ma, Dawei [3 ]
Rao, Zihe [1 ,2 ,9 ,10 ,11 ]
Yang, Haitao [1 ,2 ]
机构：
[1] ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai 201210, Peoples R China
[2] ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
[3] Univ Chinese Acad Sci, Chinese Acad Sci, State Key Lab Bioorgan & Nat Prod Chem, Ctr Excellence Mol Synth,Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
[4] Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, CAS Ctr Excellence Mol Cell Sci, Shanghai 200031, Peoples R China
[5] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[6] Chinese Acad Sci, Wuhan Inst Virol, Ctr Biosafety Mega Sci, State Key Lab Virol, Wuhan 430071, Peoples R China
[7] Chinese Acad Sci, Shanghai Adv Res Inst, Zhangjiang Lab, Natl Facil Prot Sci Shanghai, Shanghai 201210, Peoples R China
[8] Cleveland Clin, Taussig Canc Ctr, Cleveland, OH 44195 USA
[9] Tsinghua Univ, Sch Life Sci & Sch Med, Lab Struct Biol, Beijing 100091, Peoples R China
[10] Nankai Univ, State Key Lab Med Chem Biol, Coll Life Sci, Frontiers Sci Ctr Cell Response, Tianjin 300071, Peoples R China
[11] Tianjin Key Lab Prot Sci, Tianjin 300071, Peoples R China
来源：
PROTEIN & CELL | 2022年 / 13卷 / 09期
基金：
国家重点研发计划;
关键词：
D O I：
10.1007/s13238-021-00883-2
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：689 / 693
页数：5
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