Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332

被引：183

作者：

Zhao, Yao ^{[1
,2
]}

Fang, Chao ^{[3
]}

Zhang, Qi ^{[1
,2
,4
,5
]}

Zhang, Ruxue ^{[6
]}

Zhao, Xiangbo ^{[3
]}

Duan, Yinkai ^{[1
,2
]}

Wang, Haofeng ^{[1
,2
]}

Zhu, Yan ^{[1
,2
]}

Feng, Lu ^{[1
,2
]}

Zhao, Jinyi ^{[1
,2
]}

Shao, Maolin ^{[1
,2
]}

Yang, Xiuna ^{[1
,2
]}

Zhang, Leike ^{[6
]}

Peng, Chao ^{[7
]}

Yang, Kailin ^{[8
]}

Ma, Dawei ^{[3
]}

Rao, Zihe ^{[1
,2
,9
,10
,11
]}

Yang, Haitao ^{[1
,2
]}

机构：

[1] ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai 201210, Peoples R China

[2] ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China

[3] Univ Chinese Acad Sci, Chinese Acad Sci, State Key Lab Bioorgan & Nat Prod Chem, Ctr Excellence Mol Synth,Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

[4] Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, CAS Ctr Excellence Mol Cell Sci, Shanghai 200031, Peoples R China

[5] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

[6] Chinese Acad Sci, Wuhan Inst Virol, Ctr Biosafety Mega Sci, State Key Lab Virol, Wuhan 430071, Peoples R China

[7] Chinese Acad Sci, Shanghai Adv Res Inst, Zhangjiang Lab, Natl Facil Prot Sci Shanghai, Shanghai 201210, Peoples R China

[8] Cleveland Clin, Taussig Canc Ctr, Cleveland, OH 44195 USA

[9] Tsinghua Univ, Sch Life Sci & Sch Med, Lab Struct Biol, Beijing 100091, Peoples R China

[10] Nankai Univ, State Key Lab Med Chem Biol, Coll Life Sci, Frontiers Sci Ctr Cell Response, Tianjin 300071, Peoples R China

[11] Tianjin Key Lab Prot Sci, Tianjin 300071, Peoples R China

来源：

PROTEIN & CELL | 2022年 / 13卷 / 09期

基金：

国家重点研发计划;

关键词：

D O I：

10.1007/s13238-021-00883-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：689 / 693

页数：5

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