Enantioselective synthesis and chiroptical properties of optically active isoflavone epoxides

被引：31
作者：
Lévai, A
Adam, W
Fell, RT
Gessner, R
Patonay, T
Simon, A
Tóth, G
机构：
[1] Lajos Kossuth Univ, Dept Organ Chem, H-4010 Debrecen, Hungary
[2] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany
[3] Tech Univ Budapest, Hungarian Acad Sci, Inst Gen & Analyt Chem, Tech Analyt Res Grp, H-1111 Budapest, Hungary
来源：
TETRAHEDRON | 1998年 / 54卷 / 43期
关键词：
D O I：
10.1016/S0040-4020(98)00793-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Enantioselective epoxidation of isoflavones 1a-f has been performed by using Mn(III)salen complexes (I,R)-3 and (S,S)-3 as catalysts and dimethyldioxirane (DMD) or NaOCl together with 4-phenylpyridine N-oxide (PPNO) axial ligand as oxygen donors to obtain nonracemic isoflavone epoxides 2a-f. With the help of circular dichroism (CD) spectra of three enantiomeric pairs, and Snatzkes inverse octant rule, the absolute configurations of these optically active isoflavone epoxides have been determined, (C) 1998 Elsevier Science Ltd. All rights reserved.
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收藏
页码：13105 / 13114
页数：10
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