hip;
joint space width;
osteoarthritis;
radiographic measurement;
smallest delectable difference;
D O I:
10.1093/rheumatology/40.4.414
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Objectives. We assessed the influence of patient positioning and radiographic procedure, and defined a smallest detectable difference (SDD) in hip osteoarthritis (OA). Methods. OA hip patients each had a standardized pelvic radiograph and, 5 min later. a modified pelvic radiograph with the feet internally rotated 5 degrees (part 1 of the study), the X-ray beam centred on the umbilicus (part 2), or another standardized pelvic radiograph (part 3). Results. Corresponding mean differences in joint space width (JSW) measurements (limits of agreement) between views were + 0.03 (- 0.53 to + 0.59), - 0.31 (- 1.15 to + 0.53) and - 0.02 (- 0.48 to + 0.44) mm. The two views differed significantly in mean JSW in part 2 of the study (P = 1.6 x 10(-4)). but not in part I (P = 0.375) and part 3 (P = 0.580). The SDD estimate was 0.46 mm. Conclusions. Modifying the X-ray beam and foot rotation increases variability in JSW measurements. Use of urograms to evaluate radiological progression should be avoided. A change greater than 0.46 mm could define radiological hip OA progression.
机构:
Pfizer Inc, Specialty Care Business Unit, Inflammat, Clin Dev & Med Affairs, New London, CT 06320 USAPfizer Inc, Specialty Care Business Unit, Inflammat, Clin Dev & Med Affairs, New London, CT 06320 USA
Le Graverand, Marie-Pierre Hellio
Mazzuca, Steve
论文数: 0引用数: 0
h-index: 0
机构:
Indiana Univ Sch Med, Dept Med, Div Rheumatol, Long Hosp, Indianapolis, IN 46202 USAPfizer Inc, Specialty Care Business Unit, Inflammat, Clin Dev & Med Affairs, New London, CT 06320 USA
Mazzuca, Steve
Duryea, Jeff
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Sch Med, Radiol Brigham & Womens Hosp, Boston, MA 02115 USAPfizer Inc, Specialty Care Business Unit, Inflammat, Clin Dev & Med Affairs, New London, CT 06320 USA
Duryea, Jeff
Brett, Alan
论文数: 0引用数: 0
h-index: 0
机构:
Optasia Med Ltd, Cheadle SK8 1AL, EnglandPfizer Inc, Specialty Care Business Unit, Inflammat, Clin Dev & Med Affairs, New London, CT 06320 USA
机构:
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USAUniv Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA
Gordon, CL
Wu, C
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h-index: 0
机构:
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USAUniv Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA
Wu, C
Peterfy, CG
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h-index: 0
机构:
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USAUniv Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA
Peterfy, CG
Li, J
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USAUniv Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA
Li, J
Duryea, J
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h-index: 0
机构:
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USAUniv Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA
Duryea, J
Klifa, C
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USAUniv Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA
Klifa, C
Genant, HK
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USAUniv Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA
机构:
Pfizer Inc, Specialty Care Business Unit, Clin Dev & Med Affairs, Inflammat, New London, CT 06320 USAPfizer Inc, Specialty Care Business Unit, Clin Dev & Med Affairs, Inflammat, New London, CT 06320 USA
Le Graverand, Marie-Pierre Hellio
Mazzuca, Steve
论文数: 0引用数: 0
h-index: 0
机构:
Indiana Univ Sch Med, Indianapolis, IN USAPfizer Inc, Specialty Care Business Unit, Clin Dev & Med Affairs, Inflammat, New London, CT 06320 USA
Mazzuca, Steve
Duryea, Jeff
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USAPfizer Inc, Specialty Care Business Unit, Clin Dev & Med Affairs, Inflammat, New London, CT 06320 USA
Duryea, Jeff
Brett, Alan
论文数: 0引用数: 0
h-index: 0
机构:
Optasia Med, Manchester, Lancs, EnglandPfizer Inc, Specialty Care Business Unit, Clin Dev & Med Affairs, Inflammat, New London, CT 06320 USA
机构:
Rhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Brown Univ, Rhode Isl Hosp, Warren Alpert Med Sch, Dept Orthopaed, Providence, RI 02903 USARhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Mehta, Nabil
Duryea, Jeffrey
论文数: 0引用数: 0
h-index: 0
机构:
Rhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Harvard Univ, Brigham & Womens Hosp, Dept Radiol, Boston, MA USARhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Duryea, Jeffrey
Badger, Gary J.
论文数: 0引用数: 0
h-index: 0
机构:
Rhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Univ Vermont, Dept Med Biostat, Burlington, VT USARhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Badger, Gary J.
Akelman, Matthew R.
论文数: 0引用数: 0
h-index: 0
机构:
Rhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Brown Univ, Rhode Isl Hosp, Warren Alpert Med Sch, Dept Orthopaed, Providence, RI 02903 USARhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Akelman, Matthew R.
Jones, Morgan H.
论文数: 0引用数: 0
h-index: 0
机构:
Rhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA
Cleveland Clin, Dept Orthopaed Surg, Cleveland, OH 44106 USARhode Isl Hosp, Suite 404,1 Hoppin St, Providence, RI 02903 USA