Autoimmunity in diabetic autonomic neuropathy: Does the immune system get on your nerves?
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Ejskjaer, NT
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Univ London Kings Coll, Sch Med & Dent, Dept Diabet, London SE5 9PJ, EnglandUniv London Kings Coll, Sch Med & Dent, Dept Diabet, London SE5 9PJ, England
Ejskjaer, NT
[1
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Zanone, MM
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Univ London Kings Coll, Sch Med & Dent, Dept Diabet, London SE5 9PJ, EnglandUniv London Kings Coll, Sch Med & Dent, Dept Diabet, London SE5 9PJ, England
Zanone, MM
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Peakman, M
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Univ London Kings Coll, Sch Med & Dent, Dept Diabet, London SE5 9PJ, EnglandUniv London Kings Coll, Sch Med & Dent, Dept Diabet, London SE5 9PJ, England
Peakman, M
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[1] Univ London Kings Coll, Sch Med & Dent, Dept Diabet, London SE5 9PJ, England
Symptomatic autonomic neuropathy is a devastating occasional complication of diabetes mellitus, especially Type 1. Although the full-blown clinical syndrome is not common, dysfunction of the autonomic nerves is detectable in up to 40 % of Type 1 diabetic patients but its aetiopathogenesis is poorly understood. There is evidence to suggest that the damage to the autonomic nerves may be immune-mediated. This evidence is reviewed in the following article. (C) 1998 John Wiley & Sons, Ltd.