Synthesis and insulin-sensitizing activity of a novel kind of benzopyran derivative

被引：45
|
作者：
Tang, L [1 ]
Yu, JH [1 ]
Leng, Y [1 ]
Feng, Y [1 ]
Yang, YS [1 ]
Ji, RY [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200031, Peoples R China
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 20期
关键词：
D O I：
10.1016/S0960-894X(03)00734-0
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of benzopyran derivatives was synthesized and their insulin-sensitizing activities were evaluated in 3T3-L1 cells. Compounds 6 and 11 exhibited more potent insulin-sensitizing activity than rosiglitazone. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3437 / 3440
页数：4
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