Infliximab-induced interstitial lung disease

被引:5
|
作者
Karampitsakos, Theodoros [1 ]
Papaioannou, Ourania [1 ]
Sampsonas, Fotios [1 ]
Tzouvelekis, Argyrios [1 ]
机构
[1] Univ Hosp Patras, Dept Resp Med, Patras, Greece
关键词
interstitial lung disease; drugs; respiratory system; biological agents; IDIOPATHIC PULMONARY-FIBROSIS; SARCOIDOSIS; UPDATE; FACTS;
D O I
10.1136/bcr-2021-245726
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 70-year-old man was referred to our respiratory department with non-productive cough over the past 6 months. High-resolution CT revealed reticular pattern with basal and peripheral predominance, centrilobular nodules and mild ground glass opacities. Serology tests were normal and bronchoalveolar lavage revealed lymphocytosis. Pulmonary function tests showed functional impairment and reduced diffusing capacity for carbon monoxide. Meticulous evaluation of patient's medical history unveiled longitudinal administration of infliximab due to diagnosis of psoriasis. The working diagnosis of drug-induced interstitial lung disease was proposed following multidisciplinary discussion. Considerable radiological and functional improvement was determined 6 months following infliximab discontinuation without implementation of corticosteroids. To this end, the patient has reported remission of cough and functional improvement.
引用
收藏
页数:3
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