A lysozyme corona complex for the controlled pharmacokinetic release of probucol from mesoporous silica particles

被引：4
|
作者：
Giri, Kalpeshkumar [1 ,2 ]
Lau, Michael [1 ]
Kuschnerus, Inga [1 ,2 ]
Moroni, Irene [1 ]
Garcia-Bennett, Alfonso E. [1 ,2 ]
机构：
[1] Macquarie Univ, Dept Mol Sci, Sydney, NSW, Australia
[2] Macquarie Univ, Ctr Nanoscale & BioPhoton, Sydney, NSW, Australia
来源：
BIOMATERIALS SCIENCE | 2020年 / 8卷 / 14期
关键词：
BIOAVAILABILITY; NANOPARTICLES; ADSORPTION; MOLECULES; PLATFORM; SBA-15;
D O I：
10.1039/d0bm00445f
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Mesoporous silica particles (MSPs) enhance the release kinetics of poorly soluble compound probucol (PB) under the influence of a pore-blocking protein corona, prepared with lysozyme protein adsorption.In vivooral administration experiments show a prolongation in the time to reach maximum systemic concentration and half-life of PB released from the lysozyme-MSP complex in comparison to the MSP alone. Specific hard protein corona complexes can act as functional diffusion barriers for the controlled release of drugs from MSP based formulations.
引用
收藏
页码：3800 / 3803
页数：4
相关论文
共 50 条
  • [41] Hybrid mesoporous silica nanocarriers with thermovalve-regulated controlled release
    Ribero, T.
    Coutinho, E.
    Rodrigues, A. S.
    Baleizao, C.
    Farinha, J. P. S.
    NANOSCALE, 2017, 9 (36) : 13485 - 13494
  • [42] Role of Drug Adsorption onto the Silica Surface in Drug Release from Mesoporous Silica Systems
    McCarthy, Carol A.
    Ahern, Robert J.
    Devine, Ken J.
    Crean, Abina M.
    MOLECULAR PHARMACEUTICS, 2018, 15 (01) : 141 - 149
  • [43] Strategies to Obtain Encapsulation and Controlled Release of Pentamidine in Mesoporous Silica Nanoparticles
    Peretti, Enrico
    Miletto, Ivana
    Stella, Barbara
    Rocco, Flavio
    Berlier, Gloria
    Arpicco, Silvia
    PHARMACEUTICS, 2018, 10 (04):
  • [44] Synthesis of pH-responsive mesoporous silica nanotubes for controlled release
    Ma, Jie
    Lin, Huiming
    Xing, Rong
    Li, Xiaofeng
    Bian, Chunhui
    Xiang, Di
    Guo, Wei
    Qu, Fengyu
    JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 2014, 69 (02) : 364 - 369
  • [45] Ordered Mesoporous Polymer-Silica Hybrid Nanoparticles as Vehicles for the Intracellular Controlled Release of Macromolecules
    Kim, Tae-Wan
    Slowing, Igor I.
    Chung, Po-Wen
    Lin, Victor Shang-Yi
    ACS NANO, 2011, 5 (01) : 360 - 366
  • [46] Redox- and Temperature-Controlled Drug Release from Hollow Mesoporous Silica Nanoparticles
    Jiao, Yunfeng
    Sun, Yangfei
    Chang, Baisong
    Lu, Daru
    Yang, Wuli
    CHEMISTRY-A EUROPEAN JOURNAL, 2013, 19 (45) : 15410 - 15420
  • [47] Drug-templated mesoporous silica nanocontainers with extra high payload and controlled release rate
    Dement'eva, O. V.
    Naumova, K. A.
    Zhigletsova, S. K.
    Klykova, M. V.
    Somov, A. N.
    Dunaytsev, I. A.
    Senchikhin, I. N.
    Volkov, V. V.
    Rudoy, V. M.
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2020, 185 (185)
  • [48] Amine-functionalized mesoporous silica KIT 6 as a controlled release drug delivery carrier
    Ayad, Mohamad M.
    Salahuddin, Nehal A.
    Abu El-Nasr, Ahmed
    Torad, Nagy L.
    MICROPOROUS AND MESOPOROUS MATERIALS, 2016, 229 : 166 - 177
  • [49] Effect of mesoporous silica@nano-bioactive glass complex particles on the durability of dentin bonding
    You, Ran
    Qi, Haowen
    Chen, Chen
    Xie, Haifeng
    MICROPOROUS AND MESOPOROUS MATERIALS, 2022, 341
  • [50] Advances in Peptide Functionalization on Mesoporous Silica Nanoparticles for Controlled Drug Release
    Hu, Jing-Jing
    Xiao, Dong
    Zhang, Xian-Zheng
    SMALL, 2016, 12 (25) : 3344 - 3359
12345