A lysozyme corona complex for the controlled pharmacokinetic release of probucol from mesoporous silica particles

被引：4
|
作者：
Giri, Kalpeshkumar [1 ,2 ]
Lau, Michael [1 ]
Kuschnerus, Inga [1 ,2 ]
Moroni, Irene [1 ]
Garcia-Bennett, Alfonso E. [1 ,2 ]
机构：
[1] Macquarie Univ, Dept Mol Sci, Sydney, NSW, Australia
[2] Macquarie Univ, Ctr Nanoscale & BioPhoton, Sydney, NSW, Australia
来源：
BIOMATERIALS SCIENCE | 2020年 / 8卷 / 14期
关键词：
BIOAVAILABILITY; NANOPARTICLES; ADSORPTION; MOLECULES; PLATFORM; SBA-15;
D O I：
10.1039/d0bm00445f
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Mesoporous silica particles (MSPs) enhance the release kinetics of poorly soluble compound probucol (PB) under the influence of a pore-blocking protein corona, prepared with lysozyme protein adsorption.In vivooral administration experiments show a prolongation in the time to reach maximum systemic concentration and half-life of PB released from the lysozyme-MSP complex in comparison to the MSP alone. Specific hard protein corona complexes can act as functional diffusion barriers for the controlled release of drugs from MSP based formulations.
引用
收藏
页码：3800 / 3803
页数：4
相关论文
共 50 条
  • [1] Lysozyme as a pH-Responsive Valve for the Controlled Release of Guest Molecules from Mesoporous Silica
    Xue, Mengjun
    Findenegg, Gerhard H.
    LANGMUIR, 2012, 28 (50) : 17578 - 17584
  • [2] Radiofrequency controlled release from mesoporous silica nano-carriers
    Soltys, Marek
    Kovatcik, Pavel
    Lhotka, Miloslav
    Ulbrich, Pavel
    Zadrazil, Ales
    Stepanek, Frantisek
    MICROPOROUS AND MESOPOROUS MATERIALS, 2016, 229 : 14 - 21
  • [3] The Controlled Release of Drugs and Bioactive Compounds from Mesoporous Silica Nanoparticles
    Chowdhury, Mohammad A.
    CURRENT DRUG DELIVERY, 2016, 13 (06) : 839 - 856
  • [4] Influence of functionalization type on controlled release of emodin from mesoporous silica
    Jangra, Suman
    Chhokar, Vinod
    Tomer, Vijay K.
    Sharma, Ashok K.
    Duhan, Surender
    JOURNAL OF POROUS MATERIALS, 2016, 23 (04) : 1047 - 1057
  • [5] Antioxidant properties of probucol released from mesoporous silica
    Lau, Michael
    Giri, Kalpeshkumar
    Garcia-Bennett, Alfonso E.
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 138
  • [6] On the growth of the soft and hard protein corona of mesoporous silica particles with varying morphology
    Kuschnerus, Inga
    Giri, Kalpeshkumar
    Ruan, Juanfang
    Huang, Yanan
    Bedford, Nicholas
    Garcia-Bennett, Alfonso
    JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2022, 612 : 467 - 478
  • [7] Cephalexin loading and controlled release studies on mesoporous silica functionalized with amino groups
    Montiel-Centeno, Kiara
    Barrera, Deicy
    Garcia-Villen, Fatima
    Sanchez-Espejo, Rita
    Borrego-Sanchez, Ana
    Rodriguez-Castellon, Enrique
    Sandri, Giuseppina
    Viseras, Cesar
    Sapag, Karim
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2022, 72
  • [8] Grafting and controlled release of antimicrobial peptides from mesoporous silica
    Bagherabadi, Mohadeseh
    Fleckenstein, Marie
    Moskalyk, Oleksandr
    Belluati, Andrea
    Avrutina, Olga
    Andrieu-Brunsen, Annette
    JOURNAL OF MATERIALS CHEMISTRY B, 2024, 12 (33) : 8167 - 8180
  • [9] Adsorption and release of ampicillin antibiotic from ordered mesoporous silica
    Nairi, Valentina
    Medda, Luca
    Monduzzi, Maura
    Salis, Andrea
    JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2017, 497 : 217 - 225
  • [10] Hybrid mesoporous silica with controlled drug release
    Almasy, Laszlo
    Putz, Ana-Maria
    Tian, Qiang
    Kopitsa, Gennady P.
    Khamova, Tamara, V
    Barabas, Reka
    Rigo, Melinda
    Bota, Attila
    Wacha, Andras
    Mirica, Marius
    Taranu, Bogdan
    Savii, Cecilia
    JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2019, 84 (09) : 1027 - 1039
12345