The Impact of Sex and Gender on Stroke

被引：241

作者：

Rexrode, Kathryn M. ^{[1
]}

Madsen, Tracy E. ^{[2
,3
]}

Yu, Amy Y. X. ^{[4
]}

Carcel, Cheryl ^{[5
]}

Lichtman, Judith H. ^{[6
]}

Miller, Eliza C. ^{[7
]}

机构：

[1] Brigham & Womens Hosp, Div Womens Hlth, Dept Med, Boston, MA 02115 USA

[2] Brown Univ, Dept Emergency Med, Div Sex & Gender Emergency Med, Warren Alpert Med Sch, Providence, RI USA

[3] Brown Univ, Dept Epidemiol, Sch Publ Hlth, Providence, RI 02912 USA

[4] Univ Toronto, Sunnybrook Hlth Sci Ctr, Dept Med Neurol, Toronto, ON, Canada

[5] Univ New South Wales, George Inst Global Hlth, Neurol Program, Sydney, NSW, Australia

[6] Yale Sch Publ Hlth, Dept Chron Dis Epidemiol, New Haven, CT USA

[7] Columbia Univ, Dept Neurol, Div Stroke & Cerebrovasc Dis, Vagelos Coll Phys & Surg, New York, NY USA

来源：

CIRCULATION RESEARCH | 2022年 / 130卷 / 04期

基金：

美国国家卫生研究院;

关键词：

gender identity; hemorrhagic stroke; ischemic stroke; sex; stroke; women; HEALTH-CARE PROFESSIONALS; ACUTE ISCHEMIC-STROKE; PREGNANCY-RELATED STROKE; RISK-FACTORS; CARDIOVASCULAR-DISEASE; UNITED-STATES; INTRACEREBRAL HEMORRHAGE; INTRACRANIAL HEMORRHAGE; CAROTID-ENDARTERECTOMY; POSTSTROKE DEPRESSION;

D O I：

10.1161/CIRCRESAHA.121.319915

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Women face a disproportionate burden of stroke mortality and disability. Biologic sex and sociocultural gender both contribute to differences in stroke risk factors, assessment, treatment, and outcomes. There are substantial differences in the strength of association of stroke risk factors, as well as female-specific risk factors. Moreover, there are differences in presentation, response to treatment, and stroke outcomes in women. This review outlines current knowledge of impact of sex and gender on stroke, as well as delineates research gaps and areas for future inquiry.

引用

页码：512 / 528

页数：17

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