Diffusion-weighted MRI of focal cystic pancreatic lesions at 3.0-Tesla: preliminary results

被引:21
作者
Mottola, Jeffrey C. [1 ]
Sahni, V. Anik [1 ]
Erturk, Sukru M. [1 ]
Swanson, Richard [2 ]
Banks, Peter A. [3 ]
Mortele, Koenraad J. [1 ]
机构
[1] Harvard Univ, Brigham & Womens Hosp, Dept Radiol, Div Abdominal Imaging & Intervent,Med Sch, Boston, MA 02115 USA
[2] Harvard Univ, Brigham & Womens Hosp, Dept Surg, Div Oncol Surg,Med Sch, Boston, MA 02115 USA
[3] Harvard Univ, Brigham & Womens Hosp, Dept Med, Div Gastroenterol,Med Sch, Boston, MA 02115 USA
来源
ABDOMINAL IMAGING | 2012年 / 37卷 / 01期
关键词
Diffusion-weighted MRI; Focal cystic pancreatic lesions; 3.0-Tesla; Intraductal papillary mucinous neoplasm; Serous cystadenoma; Inflammatory cystic lesions; MUCIN-PRODUCING TUMOR; IMAGE QUALITY; 1.5; TESLA; NEOPLASMS; COEFFICIENT; ABDOMEN; DIFFERENTIATION; MANAGEMENT; DIAGNOSIS; VALUES;
D O I
10.1007/s00261-011-9737-6
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
To determine the utility of 3.0-Tesla diffusion-weighted (DW) magnetic resonance imaging (MRI) for focal cystic pancreatic lesion (FCPL) characterization. 55 FCPL (34 IPMN, 5 serous cystadenoma, and 16 inflammatory) were evaluated. Two radiologists reviewed in consensus DW-MRI images. Reference standard was obtained from patient history, cytological and histopathology data, FCPL fluid analysis, and follow-up imaging results. Signal intensity (SI) and apparent diffusion coefficient values (ADC) of FCPL and normal pancreas were measured. FCPL-to-pancreas SI and ADC ratios were also calculated. Qualitatively, 11 of 21 non-mucinous vs. 4 of 34 mucinous lesions appeared hyperintense at b value of 1,000 s/mm(2) (P = 0.02). Three FCPL demonstrated restricted diffusion: all inflammatory. Significant differences in mean ADC between neoplastic vs. non-neoplastic (P = 0.009), and mucinous vs. non-mucinous (P = 0.013) lesions were demonstrated. FCPL-to-pancreas ADC and SI ratios demonstrated significant differences between neoplastic vs. non-neoplastic lesions [ADC, (P = 0.019); SI for b values 750 (P = 0.010) and 1,000 s/mm(2) (P = 0.017)] and mucinous vs. non-mucinous lesions [ADC (P = 0.018); SI for b values 750 (P = 0.013) and 1,000 s/mm(2) (P = 0.015)]. Although mean ADC values and FCPL-to-pancreas SI and ADC ratios may be helpful in differentiating FCPL, characterization of individual FCPL by means of 3.0-Tesla DW-MRI appears limited.
引用
收藏
页码:110 / 117
页数:8
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