The Menopausal Transition and Cardiovascular Risk

被引：48

作者：

Chae, Claudia U. ^{[1
]}

Derby, Carol A. ^{[2
,3
,4
,5
]}

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Med,Cardiol Div, Boston, MA 02114 USA

[2] Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10461 USA

[3] Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10461 USA

[4] Albert Einstein Coll Med, Dept Epidemiol, Bronx, NY 10461 USA

[5] Albert Einstein Coll Med, Dept Populat Hlth, Bronx, NY 10461 USA

来源：

OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA | 2011年 / 38卷 / 03期

基金：

美国国家卫生研究院;

关键词：

Lipids; Blood pressure; Diabetes; Metabolic syndrome; Menopause; Perimenopause; CORONARY-HEART-DISEASE; POSTMENOPAUSAL HORMONE-THERAPY; BODY-MASS INDEX; WOMENS HEALTH; METABOLIC SYNDROME; BLOOD-PRESSURE; ENDOTHELIAL DYSFUNCTION; PERIMENOPAUSAL WOMEN; AORTIC CALCIFICATION; REPLACEMENT THERAPY;

D O I：

10.1016/j.ogc.2011.05.005

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The incidence of cardiovascular disease, which is the leading single cause of death among women, increases substantially after menopause. This may be related to adverse changes in cardiovascular risk factors that occur during the menopausal transition. Proatherogenic changes in lipid and apolipoprotein profiles seem to be specifically related to ovarian aging; unfavorable changes in other cardiovascular risk factors may be influenced more by chronologic aging. Whether these changes are due to aging or to menopause itself, increased attention to risk factor modification in the pre- and perimenopausal years will help reduce future cardiovascular disease risk among women.

引用

页码：477 / +

页数：13

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