Scutellarin inhibits translocation of protein kinase C in diabetic thoracic aorta of the rat

被引：18
|
作者：
Su, Yingxue [1 ]
Liu, Wei [1 ]
Ma, Li [1 ]
Liu, Xiaochang [1 ]
Liu, Zhaochun [1 ]
Zhu, Banghao [1 ]
机构：
[1] Sun Yat Sen Univ, Zhongshan Sch Med, Dept Pharmacol, Cardiac & Cerebral Vasc Res Ctr, Guangzhou 510080, Guangdong, Peoples R China
来源：
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | 2012年 / 39卷 / 02期
关键词：
protein kinase C; scutellarin; thoracic aortic smooth muscle cells; translocation; HIGH GLUCOSE; VASCULAR COMPLICATIONS; ACTIVATION; EXPRESSION; CELLS; DELTA; PATHOPHYSIOLOGY; RETINOPATHY; APOPTOSIS; ISOFORMS;
D O I：
10.1111/j.1440-1681.2011.05645.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
1. The aims of the present study were to explore the effects of: (i) scutellarin (Scu) on protein kinase C (PKC) translocation caused by diabetic conditions in diabetic rat thoracic aorta; and (ii) phorbol-12-myristate-13-acetate (PMA) treatment of cultured thoracic aortic smooth muscle cells.
引用
收藏
页码：136 / 140
页数：5
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