Transgender Women Living with HIV Frequently Take Antiretroviral Therapy and/or Feminizing Hormone Therapy Differently Than Prescribed Due to Drug-Drug Interaction Concerns

被引：45
作者：
Braun, Hannan M. [1 ,2 ]
Candelario, Jury [3 ]
Hanlon, Courtney L. [4 ]
Segura, Eddy R. [2 ,5 ]
Clark, Jesse L. [2 ]
Currier, Judith S. [2 ]
Lake, Jordan E. [2 ,6 ]
机构：
[1] Univ Calif San Francisco, Sch Med, San Francisco, CA USA
[2] David Geffen Sch Med, South Amer Program HIV Prevent Res, Div Infect Dis, Dept Med, Los Angeles, CA USA
[3] APAIT, Special Serv Grp, Los Angeles, CA USA
[4] Dartmouth Coll, Geisel Sch Med, Hanover, NH 03755 USA
[5] Univ Peruana Ciencias Aplicadas, Escuela Med, Lima, Peru
[6] Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Dept Internal Med, Div Infect Dis, Houston, TX 77030 USA
来源：
LGBT HEALTH | 2017年 / 4卷 / 05期
关键词：
antiretroviral therapy; health disparities; HIV; medication adherence; transgender; CARDIOVASCULAR-DISEASE; INFECTED PATIENTS; VIRAL LOAD; TRANSMISSION; MORTALITY; ADHERENCE; RISK; CARE; RESISTANCE; BARRIERS;
D O I：
10.1089/lgbt.2017.0057
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Purpose: Both hormone therapy (HT) and antiretroviral therapy (ART) can be lifesaving for transgender women (TW) living with HIV, but each has side effects and potential drug-drug interactions (DDI). We assessed how concerns about HT-ART interactions affect treatment adherence. Methods: This study used a cross-sectional survey of TW (n = 87) in Los Angeles, CA. Results: Fifty-four percent were living with HIV; 64% used HT. Only 49% of TW living with HIV discussed ART-HT DDI with their provider; 40% reported not taking ART (12%), HT (12%), or both (16%) as directed due to DDI concerns. Conclusion: Imperfect HT/ART use and limited provider communication suggests a need for improved HT-ART integration.
引用
收藏
页码：371 / 375
页数：5
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