Transgender Women Living with HIV Frequently Take Antiretroviral Therapy and/or Feminizing Hormone Therapy Differently Than Prescribed Due to Drug-Drug Interaction Concerns

被引：48

作者：

Braun, Hannan M. ^{[1
,2
]}

Candelario, Jury ^{[3
]}

Hanlon, Courtney L. ^{[4
]}

Segura, Eddy R. ^{[2
,5
]}

Clark, Jesse L. ^{[2
]}

Currier, Judith S. ^{[2
]}

Lake, Jordan E. ^{[2
,6
]}

机构：

[1] Univ Calif San Francisco, Sch Med, San Francisco, CA USA

[2] David Geffen Sch Med, South Amer Program HIV Prevent Res, Div Infect Dis, Dept Med, Los Angeles, CA USA

[3] APAIT, Special Serv Grp, Los Angeles, CA USA

[4] Dartmouth Coll, Geisel Sch Med, Hanover, NH 03755 USA

[5] Univ Peruana Ciencias Aplicadas, Escuela Med, Lima, Peru

[6] Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Dept Internal Med, Div Infect Dis, Houston, TX 77030 USA

来源：

LGBT HEALTH | 2017年 / 4卷 / 05期

关键词：

antiretroviral therapy; health disparities; HIV; medication adherence; transgender; CARDIOVASCULAR-DISEASE; INFECTED PATIENTS; VIRAL LOAD; TRANSMISSION; MORTALITY; ADHERENCE; RISK; CARE; RESISTANCE; BARRIERS;

D O I：

10.1089/lgbt.2017.0057

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Purpose: Both hormone therapy (HT) and antiretroviral therapy (ART) can be lifesaving for transgender women (TW) living with HIV, but each has side effects and potential drug-drug interactions (DDI). We assessed how concerns about HT-ART interactions affect treatment adherence. Methods: This study used a cross-sectional survey of TW (n = 87) in Los Angeles, CA. Results: Fifty-four percent were living with HIV; 64% used HT. Only 49% of TW living with HIV discussed ART-HT DDI with their provider; 40% reported not taking ART (12%), HT (12%), or both (16%) as directed due to DDI concerns. Conclusion: Imperfect HT/ART use and limited provider communication suggests a need for improved HT-ART integration.

引用

页码：371 / 375

页数：5

共 29 条

[1]

[Anonymous], GUID PRIM GEND AFF C

[2] Worldwide burden of HIV in transgender women: a systematic review and meta-analysis [J].