N-Bromosuccinimide-Mediated Synthesis of Substituted Quinoxalines

被引：19

作者：

Chan, Chieh-Kai ^{[1
]}

Chang, Meng-Yang ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 80708, Taiwan

来源：

SYNTHESIS-STUTTGART | 2016年 / 48卷 / 21期

关键词：

one-pot synthesis; N-bromosuccinimide; acetic acid; phenylacetylene; quinoxalines; ONE-POT SYNTHESIS; CATALYZED SYNTHESIS; EFFICIENT SYNTHESIS; BIOLOGICAL EVALUATION; O-PHENYLENEDIAMINE; DERIVATIVES; OXIDATION; ALKYNES; KETONES; 1,2-DIKETONES;

D O I：

10.1055/s-0035-1561472

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and simple N-bromosuccinimide-mediated two-step synthesis of substituted quinoxalines from 1,2-diarylacetylenes and 1,2-diaminobenzenes in boiling AcOH, during a one-pot procedure has been developed. All the structures of the substituted quinoxalines were confirmed, some by single-crystal X-ray crystallography. Possible reaction pathways were discussed, and some data were matched with the previous work.

引用

页码：3785 / 3793

页数：9

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