Addison's disease, diffuse skin, and mucosal hyperpigmenation with subtle "flu-like" symptoms - A report of two cases

被引：3

作者：

Burk, Cynthia J. ^{[1
]}

Ciocca, Giovanna ^{[1
]}

Heath, Candrice R. ^{[1
]}

Duarte, Anna ^{[1
]}

Dohil, Magdalene ^{[1
]}

Connelly, Elizabeth Alvarez ^{[1
]}

机构：

[1] Univ Miami, Miller Sch Med, Div Pediat Dermatol, Dept Dermatol & Cutaneous Surg, Miami, FL 33152 USA

来源：

PEDIATRIC DERMATOLOGY | 2008年 / 25卷 / 02期

关键词：

D O I：

10.1111/j.1525-1470.2008.00637.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Addison's disease, or chronic adrenocortical insufficiency, is the overproduction of adrenocorticotropic hormone by the pituitary gland as a compensatory mechanism for decreased cortisol production by the adrenal glands. Classically, patients affected with Addison's disease develop weakness, anorexia, electrolyte imbalances: decreased sodium and chloride with increased serum potassium resulting in hypotension, and hyperpigmentation of the skin and mucous membranes. Herein this case report, we focus on the subtle findings of diffuse hyperpigmentation and intermittent but repetitive "flu-like" symptoms in two patients to correctly identify the diagnosis of Addison's disease effectively and efficiently.

引用

页码：215 / 218

页数：4

共 17 条

[1]

Addison T., 1855, CONSTITUTIONAL LOCAL

[2] GLUCOCORTICOID THERAPY [J].