Changes in portal hemodynamics and acute rejection in the first 2 weeks after orthotopic liver transplantation - A prospective Doppler ultrasound study

被引:12
作者
Kok, T
Slooff, MJH
Peeters, PMJG
Zwaveling, JH
Bijleveld, CMA
GiVanLoon, CETP
Klompmaker, IJ
Haagsma, EB
机构
[1] UNIV GRONINGEN HOSP,DEPT SURG,NL-9700 RB GRONINGEN,NETHERLANDS
[2] UNIV GRONINGEN HOSP,DEPT PEDIAT,NL-9700 RB GRONINGEN,NETHERLANDS
[3] UNIV GRONINGEN HOSP,DEPT INTERNAL MED,NL-9700 RB GRONINGEN,NETHERLANDS
关键词
liver transplantation; Doppler ultrasound; rejection; portal vein;
D O I
10.1097/00004424-199612000-00007
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
RATIONALE AND OBJECTIVES. To analyze changes in Doppler ultrasound variables of the portal vein in relation to liver biopsy findings, the authors performed a prospective study of 316 Doppler ultrasound examinations in the first 2 weeks after orthotopic liver transplantation on 23 patients. METHODS. Recordings were obtained daily from the portal vein (diameter, maximum velocity, and how), Correlations were explored between the Doppler ultrasound findings and histologic data. The chi-square test was used to analyze differences in Doppler ultrasound variables in patients Kith and without acute rejection. RESULTS. In our series of 23 patients, acute rejection was diagnosed by liver biopsy in nine of them (39%), Changes in portal vein diameter, maximum velocity, and flow did not correlate consistently with liver biopsy findings, due to a multifactorial origin, Changes in portal hemodynamics were observed in patients with hepatic artery thrombosis, portal vein stenosis, acute rejection, and sepsis. CONCLUSIONS. Although routine screening using Doppler ultrasound proved to be useful for the determination of rapid changes in portal hemodynamics within a short time, serial Doppler ultrasound examinations were not helpful in predicting acute rejection.
引用
收藏
页码:774 / 780
页数:7
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