The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures

被引：223

作者：

Andreeva, Antonina ^{[1
]}

Kulesha, Eugene ^{[2
]}

Gough, Julian ^{[1
]}

Murzin, Alexey G. ^{[1
]}

机构：

[1] MRC Lab Mol Biol, Francis Crick Ave, Cambridge CB2 0QH, England

[2] EKMM Ltd, Cambridge CB1 9AZ, England

来源：

NUCLEIC ACIDS RESEARCH | 2020年 / 48卷 / D1期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

SEQUENCES;

D O I：

10.1093/nar/gkz1064

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Structural Classification of Proteins (SCOP) database is a classification of protein domains organised according to their evolutionary and structural relationships. We report a major effort to increase the coverage of structural data, aiming to provide classification of almost all domain super-families with representatives in the PDB. We have also improved the database schema, provided a new API and modernised the web interface. This is by far the most significant update in coverage since SCOP 1.75 and builds on the advances in schema from the SCOP 2 prototype.

引用

页码：D376 / D382

页数：7

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