Arylation of Adamantanamines: III. Palladium-Catalyzed Arylation of Adamantane-1,3-diyldimethanamine and 2,2′-(Adamantane-1,3-diyl)diethanamine

被引：9

作者：

Averin, A. D. ^{[1
]}

Ulanovskaya, M. A. ^{[1
]}

Buryak, A. K. ^{[2
]}

Savel'ev, E. N. ^{[3
]}

Orlinson, B. S. ^{[3
]}

Novakov, I. A. ^{[3
]}

Beletskaya, I. P. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Chem, Moscow 119992, Russia

[2] Russian Acad Sci, Frumkin Inst Phys Chem & Electrochem, Moscow, Russia

[3] Volgograd State Tech Univ, Volgograd, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 47卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

AMINATION; DIHALOBENZENES; COMPLEXES; FAMILY;

D O I：

10.1134/S1070428011010027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed arylation of adamantane-1,3-diyldimethanamine and 2,2'-(adamantane-1,3-diyl)diethanamine with isomeric bromochloro- and dibromobenzenes was studied. The yields of N,N'-diarylation products depend on the initial diamine and dihalobenzene structure. Side reactions were revealed, which reduced the yield of the target products. The arylation of 2,2'-(adamantane-1,3-diyl) diethanamine gives the corresponding N,N'-diaryl derivatives with better yield. The possibility for synthesizing unsymmetrical N, N'-diaryl derivatives of 2,2'-(adamantane-1,3-diyl) diethanamine was demonstrated.

引用

页码：30 / 40

页数：11

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