Synthetic strategies towards the synthesis of 1-(2,4-dideoxy-4-C-hydroxymethyl-α-L-lyxopyranosyl)base nucleosides.

被引：2

作者：

Turner, SJ ^{[1
]}

Herdewijn, P ^{[1
]}

机构：

[1] Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 1998年 / 17卷 / 9-11期

关键词：

D O I：

10.1080/07328319808004750

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A synthetic strategy towards the synthesis of 1-(2,4-dideoxy-4-C-hydroxymethyl-alpha-L-lyxopyranosyl)thymine by the formation and Opening of a 3,4-anhydropentopyranose sugar is described.

引用

页码：2085 / 2086

页数：2

共 50 条

[1] Synthesis and conformational analysis of 1-[2,4-dideoxy-4-C-hydroxymethyl-α-L-lyxopyranosyl]thymine
Vanheusden, V
Busson, R
Herdewijn, P
Van Calenbergh, S
JOURNAL OF ORGANIC CHEMISTRY, 2004, 69 (13): : 4446 - 4453
[2] Synthesis and biological evaluation of novel 2,4-dideoxy-4-C-hydroxymethyl-α, β-L-lyxopyranosyl-pyrimidine and -purine nucleosides.
Stemphoski, AM
Montgomery, JA
Secrist, JA
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U164 - U164
[3] SYNTHESIS OF 1-(3-AZIDO-2,3-DIDEOXY-4-C-HYDROXYMETHYL-ALPHA-L-THREO-PENTOFURANOSYL)THYMINE, 1-(2,3-DIDEOXY-4-C-HYDROXYMETHYL-ALPHA-L-GLYCERO-PENTOFURANOSYL)THYMINE AND 1-(2,3-DIDEOXY-4-C-HYDROXYMETHYL-ALPHA-L-GLYCERO-PENT-2-ENOFURANOSYL)THYMINE
HREBABECKY, H
HOLY, A
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1993, 58 (02) : 409 - 420
[4] Divergent synthesis of D- and L-4'-fluorocarbocyclic 2′,3′-dideoxy nucleosides.
Gumina, G
Chong, YH
Chu, GK
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 219 : U102 - U102
[5] Synthesis of 2′,3′-dideoxy-3′-C-(hydroxymethyl)-4′-thiopentofuranosyl nucleosides as potential antiviral agent
Ichikawa, E
Yamamura, S
Kato, K
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (08) : 1113 - 1114
[6] SYNTHESIS OF 2',3'-DIDEOXY-3'-C-HYDROXYMETHYL NUCLEOSIDES HAVING THE L-CONFIGURATION AS POTENTIAL INHIBITORS OF HIV
KVARNSTROM, I
SVANSSON, L
SVENSSON, C
SVENSSON, SCT
CLASSON, B
SAMUELSSON, B
NUCLEOSIDES & NUCLEOTIDES, 1992, 11 (07): : 1367 - 1370
[7] Acyclic analogs of pyrimidine nucleosides. Synthesis of 1-(2-hydroxyethoxymethyl)- and 1-(4-hydroxybutyl)-5-amino derivatives of uracil
Novikov M.S.
Ozerov A.A.
Chemistry of Heterocyclic Compounds, 1998, 34 (7) : 841 - 847
[8] Acyclic analogs of pyrimidine nucleosides. Synthesis of 1-(2-hydroxyethoxymethyl)- and 1-(4-hydroxybutyl)-5-amino derivatives of uracil
Scientific-Research Institute of Pharmacology, Volgograd Medical Academy, Volgograd 400066, Russia
Chemistry of Heterocyclic Compounds, 1998, 34 (07): : 841 - 847
[9] Acyclic analogs of pyrimidine nucleosides. Synthesis of uracil 1-(2-hydroxyethoxy)methyl- and 1-(4-hydroxybutyl)-5-amino derivatives
Novikov, MS
Ozerov, AA
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1998, (07): : 971 - 978
[10] Hydroxymethyl-Branched Piperidines from Hydroxymethyl-Branched Lactones: Synthesis and Biological Evaluation of 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-D-mannitol, 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-L-gulitol and 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-D-talitol
Soengas, Raquel G.
Simone, Michela I.
Hunter, Stuart
Nash, Robert J.
Evinson, Emma L.
Fleet, George W. J.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2012, 2012 (12) : 2394 - 2402

← 1 2 3 4 5 →