A sham stimulation-controlled trial of rTMS of the unaffected hemiphere in stroke patients

被引：415
作者：
Mansur, CG
Fregni, F
Boggio, PS
Riberto, M
Gallucci-Neto, J
Santos, CM
Wagner, T
Rigonatti, SP
Marcolin, MA
Pascual-Leone, A
机构：
[1] Harvard Univ, Ctr Noninvas Brain Stimulat, Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
[2] Univ Sao Paulo, Dept Phys Med & Rehabil, Sao Paulo, Brazil
[3] Univ Sao Paulo, Inst Psychiat, Sao Paulo, Brazil
来源：
NEUROLOGY | 2005年 / 64卷 / 10期
关键词：
D O I：
10.1212/01.WNL.0000161839.38079.92
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors investigated the use of slow-frequency repetitive transcranial magnetic stimulation (rTMS) to the unaffected hemisphere to decrease interhemispheric inhibition of the lesioned hemisphere and improve motor function in patients within 12 months of a stroke. Patients showed a significant decrease in simple and choice reaction time and improved performance of the Purdue Pegboard test with their affected hand after rTMS of the motor cortex in the intact hemisphere as compared with sham rTMS.
引用
收藏
页码：1802 / 1804
页数：3
相关论文
共 10 条
[1]   Motor cortex stimulation for enhancement of recovery after stroke: Case report [J].
Brown, JA ;
Lutsep, H ;
Cramer, SC ;
Weinand, M .
NEUROLOGICAL RESEARCH, 2003, 25 (08) :815-818
[2]   Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation [J].
Chen, R ;
Classen, J ;
Gerloff, C ;
Celnik, P ;
Wassermann, EM ;
Hallett, M ;
Cohen, LG .
NEUROLOGY, 1997, 48 (05) :1398-1403
[3]   Repetitive TMS of the motor cortex improves ipsilateral sequential simple finger movements [J].
Kobayashi, M ;
Hutchinson, S ;
Théoret, H ;
Schlaug, G ;
Pascual-Leone, A .
NEUROLOGY, 2004, 62 (01) :91-98
[4]  
LEVY R, 2004, NEUR M 2004 BIENN M
[5]   Training-induced changes of motor cortex representations in stroke patients [J].
Liepert, J ;
Graef, S ;
Uhde, I ;
Leidner, O ;
Weiller, C .
ACTA NEUROLOGICA SCANDINAVICA, 2000, 101 (05) :321-326
[6]   Motor cortex plasticity during forced-use therapy in stroke patients:: a preliminary study [J].
Liepert, J ;
Uhde, I ;
Gräf, S ;
Leidner, O ;
Weiller, C .
JOURNAL OF NEUROLOGY, 2001, 248 (04) :315-321
[7]  
Martin Paula I., 2004, Seminars in Speech and Language, V25, P181
[8]   Left frontal transcranial magnetic stimulation reduces contralesional extinction in patients with unilateral right brain damage [J].
Oliveri, M ;
Rossini, PM ;
Traversa, R ;
Cicinelli, P ;
Filippi, MM ;
Pasqualetti, P ;
Tomaiuolo, F ;
Caltagirone, C .
BRAIN, 1999, 122 :1731-1739
[9]   Mechanisms underlying recovery of motor function after stroke [J].
Ward, NS ;
Cohen, LG .
ARCHIVES OF NEUROLOGY, 2004, 61 (12) :1844-1848
[10]   Contribution of the ipsilateral motor cortex to recovery after chronic stroke [J].
Werhahn, KJ ;
Conforto, AB ;
Kadom, N ;
Hallett, M ;
Cohen, LG .
ANNALS OF NEUROLOGY, 2003, 54 (04) :464-472
1