The loss of function induced by HERG and KVLQT1 mutations does not correlate with the clinical severity of the long QT syndrome

被引：0
|
作者：
Priori, SG
Napolitano, C
Brown, AM
Bianchi, L
Taglialatela, M
Ronchetti, E
Castaldo, P
Bloise, R
Schwartz, PJ
机构：
[1] Fdn S Maugeri, Pavia, Italy
[2] Case Western Reserve Univ, Rammelkamp Res Ctr, Cleveland, OH 44106 USA
[3] Univ Naples Federico II, Dept Neurosci, Pharmacol Sect, Naples, Italy
[4] Univ Pavia, I-27100 Pavia, Italy
来源：
CIRCULATION | 1998年 / 98卷 / 17期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2405
引用
收藏
页码：457 / 457
页数：1
相关论文
共 50 条
  • [21] Two novel point mutations in the same fragment of KvLQT1 gene causing long QT (Romano-Ward) syndrome
    Trinity, E
    Steen, J
    Apple, FS
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2002, 118 (02) : 297 - 298
  • [22] Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome
    Itoh, T
    Tanaka, T
    Nagai, R
    Kikuchi, K
    Ogawa, S
    Okada, S
    Yamagata, S
    Yano, K
    Yazaki, Y
    Nakamura, Y
    HUMAN GENETICS, 1998, 103 (03) : 290 - 294
  • [23] Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome
    Toshio Itoh
    T. Tanaka
    Ryozo Nagai
    Kenjiro Kikuchi
    Satoshi Ogawa
    Shintaro Okada
    Shiro Yamagata
    Katsusuke Yano
    Yoshio Yazaki
    Yusuke Nakamura
    Human Genetics, 1998, 103 : 290 - 294
  • [24] Novel donor splice site mutation in the KVLQT1 gene is associated with long QT syndrome
    Kanters, JK
    Larsen, LA
    Orholm, M
    Agner, E
    Andersen, PS
    Vuust, J
    Christiansen, M
    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 1998, 9 (06) : 620 - 624
  • [25] Molecular genetics of the long QT syndrome: Two novel mutations of the KVLQT1 gene and phenotypic expression of the mutant gene in a large kindred
    Saarinen, K
    Swan, H
    Kainulainen, K
    Toivonen, L
    Viitasalo, M
    Kontula, K
    HUMAN MUTATION, 1998, 11 (02) : 158 - 165
  • [26] A novel mutation in the KvLQT1 gene leading to a relatively benign form of Long QT Syndrome.
    Kanters, JK
    Larsen, LA
    Andersen, PS
    Vuust, J
    Christiansen, M
    CIRCULATION, 1998, 98 (17) : 457 - 458
  • [27] HERG and KvLQT1/IsK, the cardiac K+ channels involved in long QT syndromes, are targets for calcium channel blockers
    Chouabe, C
    Drici, MD
    Romey, G
    Barhanin, J
    Lazdunski, M
    MOLECULAR PHARMACOLOGY, 1998, 54 (04) : 695 - 703
  • [28] Functional expression of a KVLQT1 missense mutation that causes a forme fruste long QT syndrome.
    Chouabe, C
    Neyroud, N
    Richard, P
    Denjoy, I
    Drici, MD
    Hainque, B
    Coumel, P
    Barhanin, J
    Guicheney, P
    CIRCULATION, 1998, 98 (17) : 468 - 469
  • [29] The long QT syndrome: a novel missense mutation in the S6 region of the KVLQT1 gene
    M. H. van den Berg
    Arthur A. M Wilde
    E. O. Robles de Medina
    Henk Meyer
    J. L. M. C. Geelen
    Roselie J. E. Jongbloed
    Hein J. J. Wellens
    Joep P. M. Geraedts
    Human Genetics, 1997, 100 : 356 - 361
  • [30] The long QT syndrome: a novel missense mutation in the S6 region of the KVLQT1 gene
    vandenBerg, MH
    Wilde, AAM
    deMedina, EOR
    Meyer, H
    Geelen, JLMC
    Jongbloed, RJE
    Wellens, HJJ
    Geraedts, JPM
    HUMAN GENETICS, 1997, 100 (3-4) : 356 - 361
12345