Synthesis and Antimicrobial Evaluation of Some New Pyrrolylnaphtho[2,1-b] furan Derivatives

被引：0

作者：

Joshi, S. D. ^{[1
]}

Ashwini, Joshi ^{[1
]}

Vagdevi, H. M. ^{[2
]}

Vaidya, V. P. ^{[3
]}

Gadaginamath, G. S. ^{[1
]}

机构：

[1] SETs Coll Pharm, Dept Pharmaceut Chem, Dharwad, Karnataka, India

[2] Sahyadri Sci Coll Autonomous, Dept Chem, Shimoga, Karnataka, India

[3] Kuvempu Univ, Sch Chem Sci, Dept PG Studies & Res Chem, Shankaraghatta, Karnataka, India

来源：

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH | 2010年 / 44卷 / 02期

关键词：

Pyrrolylnaphtho[2,1-b] furans; Antimicrobial and Antifungal activity; Broth microdilution assay method;

D O I：

暂无

中图分类号：

G40 [教育学];

学科分类号：

040101 ; 120403 ;

摘要：

A series of new (3-substitutedphenyl-5-hydroxy-5-naphtho[ 2,1-b] furan-2-yl-4,5-dihydropyrazol- 1-yl)-(4-pyrrol-1-ylphenyl) methanones have been synthesized. The structures of these compounds were established on the basis of spectral data and elemental analysis. All the compounds were evaluated for antibacterial and antifungal activities by the broth microdilution assay method. All the compounds were found moderately active.

引用

页码：148 / 155

页数：8

共 11 条

[1] Synthesis, structural activity relationship and anti-tubercular activity of novel pyrazoline derivatives [J].

Ali, Mohamed Ashraf ;

Shaharyar, Mohammad ;

Siddiqui, Anees Ahamed .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 42 (02) :268-275

[2] Syntheses, characterization and in vitro antiamoebic activity of new Pd(II) complexes with 1-N-substituted thiocarbamoyl-3,5-diphenyl-2-pyrazoline derivatives [J].

Budakoti, Asha ;

Abid, Mohammad ;

Azam, Amir .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 42 (04) :544-551

[3]

CHIARINI A, 1979, FARMACO-ED SCI, V34, P125

[4]

GIOVANNINETTI G, 1981, FARMACO-ED SCI, V36, P94

[5]

Goto S.K., 1981, Chemotherapy, V29, P76

[6] Synthesis of new 4-pyrrol-1-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: A novel class of potential antibacterial and antitubercular agents [J].

Joshi, S. D. ;

Vagdevi, H. M. ;

Vaidya, V. P. ;

Gadaginamath, G. S. .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (09) :1989-1996

[7] Synthesis and cytotoxic evaluation of α-methylene-γ-butyrolactone bearing naphthalene and naphtho[2,1-b]furan derivatives [J].

Lee, KH ;

Huang, BR .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2002, 37 (04) :333-338

[8] Synthesis and antidepressant activities of some 3,5-diphenyl-2-pyrazolines [J].

Palaska, E ;

Aytemir, M ;

Uzbay, IT ;

Erol, D .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2001, 36 (06) :539-543

[9] Synthesis of 1-(3′,4′,5′-trimethoxy) phenyl naphtho[2,1b]furan as a novel anticancer agent [J].

Srivastava, V ;

Negi, AS ;

Kumar, JK ;

Faridi, U ;

Sisodia, BS ;

Darokar, MP ;

Luqman, S ;

Khanuja, SPS .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (04) :911-914

[10] Synthesis of some thiazolyl-pyrazoline derivatives and preliminary investigation of their hypotensive activity [J].

Turan-Zitouni, G ;

Chevallet, P ;

Kiliç, FS ;

Erol, K .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2000, 35 (06) :635-641

← 1 2 →