In order to increase the core competence, logistics service supply chain should not only effectively collect, transfer, clean up and share all kinds of data and information, but also make the best use of them in the decision-making process. It should be noted that decision support system (DSS) is an important guarantee for logistics service supply chain to make a right and real-time decision. In light of the practice in integration of logistics service and the designing principle of DSS, the paper analyses and discusses about the objective design, structural design and functional design of DSS for logistics service supply chain in detail. At the same time, we address ourselves to the full decision-making process by synthetically using many technologies, such as data warehouse, data mining and on-line analysis process.