Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease

被引：9

作者：

Vos, Miriam B. ^{[1
]}

Dimick-Santos, Lara ^{[2
]}

Mehta, Ruby ^{[2
]}

Omokaro, Stephanie O. ^{[2
]}

Taminiau, Johannes ^{[3
,45
]}

Schabel, Elmer ^{[4
]}

Kleiner, David E. ^{[5
,32
]}

Szitanyi, Peter ^{[6
,44
]}

Socha, Piotr ^{[7
]}

Schwimmer, Jeffrey B. ^{[8
,16
,42
]}

Noviello, Stephanie ^{[9
]}

Silberg, Debra G. ^{[10
]}

Torstenson, Richard ^{[11
]}

Miller, Veronica ^{[12
]}

Lavine, Joel E. ^{[13
]}

Adda, Nathalie ^{[14
]}

Baldyga, William

Banerjee, Rajarshi ^{[15
]}

Behling, Cynthia ^{[16
]}

Boulos, Sherif ^{[17
]}

Burgess, Gary ^{[18
]}

Calboli, Dania ^{[19
]}

Charles, Edgar ^{[9
]}

Christian, Rose ^{[9
]}

Cohen-Bacrie, Claude ^{[20
]}

Cosma-Roman, Doina ^{[21
]}

Danzer, Claus-Peter ^{[19
]}

Delaet, Ingrid ^{[22
]}

Delegge, Mark ^{[23
]}

Dimick-Santos, Lara ^{[2
]}

DiProspero, Nicholas ^{[24
]}

Donohue, Kathleen ^{[2
]}

Fischer, Laurent ^{[25
]}

Fitzpatrick, Emer ^{[26
]}

Fried, Michael ^{[27
]}

Hagerty, David ^{[28
]}

Hale, Paula ^{[11
]}

Hildick, Keri ^{[15
]}

Hum, Dean ^{[29
]}

Jamil, Khurram ^{[30
]}

Jiang, Lijuan ^{[14
]}

Karpen, Saul ^{[31
]}

Kelly, Matt ^{[15
]}

Kleiner, David E. ^{[5
,32
]}

Kohli, Rohit ^{[33
]}

Kordy, Kattayoun ^{[34
]}

Krieger, Nancy ^{[19
]}

Lavine, Joel ^{[35
]}

Lee, Lois ^{[22
]}

Lefebvre, Eric ^{[25
]}

机构：

[1] Emory Univ, Sch Med, Atlanta, GA 30322 USA

[2] US FDA, Bethesda, MD 20014 USA

[3] Antwerp Univ Hosp, Antwerp, Belgium

[4] Bundesinst Arzneimittel & Med Prod, Bonn, Germany

[5] NCI, Ctr Canc Res, Bethesda, MD 20892 USA

[6] Charles Univ Prague, Gen Univ Hosp, Prague, Czech Republic

[7] Childrens Mem Hlth Inst, Warsaw, Poland

[8] Univ Calif San Diego, Sch Med, La Jolla, CA 92093 USA

[9] Bristol Myers Squibb, New York, NY USA

[10] Takeda Pharmaceut, Tokyo, Japan

[11] Novo Nordisk AS, Bagsvaerd, Denmark

[12] Forum Collaborat Res, Berkeley, CA USA

[13] Columbia Univ, Med Ctr, New York, NY USA

[14] Enanta Pharmaceut Inc, Watertown, MA USA

[15] Perspectum Diagnost Ltd, Oxford, England

[16] Univ Calif San Diego, La Jolla, CA 92093 USA

[17] Resonance Hlth, Burswood, WA, Australia

[18] Vectura Ltd, Chippenham, England

[19] Novartis Pharma AG, Basel, Switzerland

[20] SuperSon Imagine, Aix En Provence, France

[21] Teva Pharmaceut, Petah Tiqwa, Israel

[22] Intercept Pharmaceut Inc, New York, NY USA

[23] QuintilesIMS, Durham, NC USA

[24] Janssen Res & Dev, Raritan, NJ USA

[25] Allergan, Dublin, Ireland

[26] Kings Coll Hosp London, Sch Med, Kings Coll London, London, England

[27] Univ N Carolina, Chapel Hill, NC 27515 USA

[28] Conatus Pharmaceut Inc, San Diego, CA USA

[29] GENFIT SA, Loos, France

[30] Mallinckrodt Pharmaceut, Staines Upon Thames, England

[31] Emory Univ, Atlanta, GA 30322 USA

[32] NCI, Bethesda, MD 20892 USA

[33] Childrens Hosp Los Angeles, Los Angeles, CA 90027 USA

[34] Novartis Pharmaceut, Basel, Switzerland

[35] Columbia Univ, New York, NY USA

[36] TARGET PharmaSolut, Durham, NC USA

[37] Raptor Pharmaceut, Novato, CA USA

[38] Afimmune Ltd, Dublin, Ireland

[39] Immuron Ltd, Blackburn North, Australia

[40] Virginia Commonwealth Univ, Richmond, VA 23284 USA

[41] Johns Hopkins Univ, Sch Med, Baltimore, MD 21218 USA

[42] Rady Childrens Hosp San Diego, San Diego, CA USA

[43] UPMC, Childrens Hosp Pittsburgh, Pittsburgh, PA USA

[44] Charles Univ Prague, Gen Univ Hosp, Fac Med 1, Prague, Czech Republic

[45] European Med Agcy, Amsterdam, Netherlands

[46] NuSirt Biopharma, Nashville, TN USA

来源：

GASTROENTEROLOGY | 2019年 / 157卷 / 06期

关键词：

HEPATIC STEATOSIS; VITAMIN-E; PROGNOSTIC-SIGNIFICANCE; CARDIOVASCULAR-DISEASE; HISTOLOGIC FEATURES; METABOLIC SYNDROME; UNITED-STATES; CHILDREN; FIBROSIS; STEATOHEPATITIS;

D O I：

10.1053/j.gastro.2019.08.048

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：1448 / +

页数：10

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