Background/Objectives Lichen planopilaris is a primary lymphocytic cicatricial alopecia. Management of patients with lichen planopilaris is difficult due to a paucity of high-quality data on its epidemiology and pathogenesis and the efficacy of therapies. The purpose of this study was to report the characteristics and treatment outcomes of patients with lichen planopilaris in a tertiary referral centre. Methods Results A retrospective review of medical records in patients with lichen planopilaris seen in the Hair Clinic at the Skin & Cancer Foundation Inc., Melbourne, from 2012 to 2016. Altogether 32 patients with lichen planopilaris (29 women) were included. The onset age ranged from 17 to 77 years with a mean age of 55.2 +/- 13.5 years. Scalp pruritus (84%) and perifollicular erythema (72%) were the most common presenting symptoms and signs, respectively. Lichen planopilaris involved the frontal scalp in 66% of patients, the parietal in 56%, and vertex scalp in 50%. There were wide variations in treatment response. Conclusion Lichen planopilaris is characterised by a marked female predominance and clinically with pruritus, perifollicular erythema and perifollicular scale. The current range of treatments used produced mixed and often unsatisfactory results. Multicentre, prospective, randomised controlled trials are warranted to provide clearer data on efficacious treatment options.
机构:
Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Karnik, Pratima
Tekeste, Zenar
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Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Tekeste, Zenar
McCormick, Thomas S.
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Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
McCormick, Thomas S.
Gilliam, Anita C.
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Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Gilliam, Anita C.
Price, Vera H.
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Univ Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Price, Vera H.
Cooper, Kevin D.
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Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Cooper, Kevin D.
Mirmirani, Paradi
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机构:
Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
机构:
Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Karnik, Pratima
Tekeste, Zenar
论文数: 0引用数: 0
h-index: 0
机构:
Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Tekeste, Zenar
McCormick, Thomas S.
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h-index: 0
机构:
Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
McCormick, Thomas S.
Gilliam, Anita C.
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h-index: 0
机构:
Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Gilliam, Anita C.
Price, Vera H.
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h-index: 0
机构:
Univ Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Price, Vera H.
Cooper, Kevin D.
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h-index: 0
机构:
Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA
Cooper, Kevin D.
Mirmirani, Paradi
论文数: 0引用数: 0
h-index: 0
机构:
Case Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USACase Western Reserve Univ, Dept Dermatol, Univ Hosp Case Med Ctr, Cleveland, OH 44106 USA