A comparison of stochastic variation in mixed and unmixed casework and synthetic samples

被引：27
作者：
Bright, Jo-Anne [1 ]
McManus, Kurt [1 ]
Harbison, SallyAnn [1 ]
Gill, Peter [2 ,3 ]
Buckleton, John [1 ]
机构：
[1] ESR, Auckland, New Zealand
[2] Univ Oslo, Inst Forens Med, N-0316 Oslo, Norway
[3] Univ Strathclyde, Ctr Forens Sci, Glasgow, Lanark, Scotland
来源：
FORENSIC SCIENCE INTERNATIONAL-GENETICS | 2012年 / 6卷 / 02期
关键词：
Mixed DNA profile; Heterozygote balance; Mixture proportion;
D O I：
10.1016/j.fsigen.2011.04.010
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Understanding the behaviour of mixed DNA profiles is of paramount importance in forensic DNA analysis. Key parameters are those of heterozygote balance and mixture proportion and its variability. These parameters have been previously explored as a function of the average peak height of the active alleles in single source and mixed samples derived from pristine DNA. Here we report a comparison of this data with data obtained from casework samples. This allows an assessment of the difference in the distribution of heterozygote balance between mixed and single source stains and between casework mixtures and synthetic mixtures constructed from pristine DNA. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：180 / 184
页数：5
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