New antisense oligonucleotide therapies reach first base in ALS

被引：8
|
作者：
Lopez, Elia R. [1 ]
Borschel, William F. [1 ]
Traynor, Bryan J. [1 ,2 ]
机构：
[1] NIH, Therapeut Dev Branch, Natl Ctr Adv Translat Sci, Rockville, MD 20852 USA
[2] NIA, Lab Neurogenet, NIH, Bethesda, MD 20892 USA
来源：
NATURE MEDICINE | 2022年 / 28卷 / 01期
基金：
美国国家卫生研究院;
关键词：
HEXANUCLEOTIDE REPEAT; SHAM CONTROL; NUSINERSEN; C9ORF72;
D O I：
10.1038/s41591-021-01629-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two studies highlight the evolution of antisense oligonucleotide therapy for amyotrophic lateral sclerosis, offering hope for an effective treatment.
引用
收藏
页码：25 / 27
页数：3
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