Monoterpene glycosides and triterpene acids from Eriobotrya deflexa

A phytochemical study on a methanolic extract of leaves of Eriobotrya deflexa led to the isolation and characterization of nine terpenoid compounds. Four of these are new chemical entities, including two monoterpene glycosides, (3S)-O-alpha -L-rhamnopyranosyl-(1-->3)-[4-O-(E)-coumaroyl]-alpha -L-rhamnopyranosyl(1-->6)-beta -D-glucopyranosyl-linalool (1) and (3S)-O-alpha -L-rhamnopyranosyl-(1-->3)-[4-O-(Z)-coumaroyl]-alpha -L-rhamnopyranosyl-(1-->6)-beta -D-glucopyranosyl-linalool (2), and two triterpene acids, 1 beta ,2 alpha ,19 alpha -trihydroxy-3-oxo-12-ursen-28-oic acid (3) and 2 alpha ,3 alpha ,19 alpha -trihydroxy-12-oleanen-28-oic acid (4). Their structures were elucidated on the basis of spectroscopic analysis. The activities of these isolates in an in vitro antiproliferation test were also determined.