Serum cortisol levels in patients with a transient global amnesia

被引：8

作者：

Schneckenburger, R. ^{[1
,2
]}

Hainselin, M. ^{[2
,3
]}

Viader, F. ^{[1
,2
]}

Eustache, F. ^{[1
,2
]}

Quinette, P. ^{[1
,2
]}

机构：

[1] CHU Caen, Caen, France

[2] PSL Res Univ, Normandie Univ, EPHE,UNICAEN, INSERM,Neuropsychol & Imagerie Memoire Humaine, Caen, France

[3] Univ Picardie Jules Verne, CRPCPO, EA 7273, Amiens, France

来源：

REVUE NEUROLOGIQUE | 2020年 / 176卷 / 04期

关键词：

Transient Global Amnesia; Cortisol; Stress; Memory;

D O I：

10.1016/j.neurol.2019.08.011

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Transient global amnesia (TGA) can be triggered by a high level of blood cortisol. We assessed whether patients had a higher level of cortisol during the TGA than shortly after. We included 52 patients, 21 with blood collected during the TGA episode and 31 shortly thereafter. We compared these two groups after adjustment for time of blood collection. The cortisol level was significantly higher in the per-ictal group (P = 0.03) and negatively correlated with the time elapsed from symptom onset (P = 0.005). The results are consistent with of the hypothesis of a hyperreactivity of the hypothalamic-pituitary-adrenal axis. (C) 2020 Elsevier Masson SAS. All rights reserved.

引用

页码：285 / 288

页数：4

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